Results 361 to 370 of about 1,846,702 (390)

Neutralization of Arenaviruses by Antibody

1987
Neutralization of infectivity is the end result of a number of alternative or synergistic reactions between a virus and antibody directed against certain antigenic determinants on its surface. These reactions prevent either the attachment of virus to a particular host cell by steric hindrance, the entry of virus into the cell, or the uncoating of the ...
openaire   +3 more sources

Protective neutralizing antibodies

Science, 2020
Coronavirus Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Rogers et al.
openaire   +2 more sources

Production of Neutralizing Antibody

Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa, Shuang, Liu
openaire   +2 more sources

Statistical issues in neutralizing antibodies

Neurology, 2003
Frequently the question of the effects of neutralizing antibodies (NAbs) is stated, but not clearly. Some ask: “Are we sure NAbs are important?” And others ask: “Are we sure NAbs are NOT important?” These two questions can lead to different statistical designs and different approaches to the investigation of the impact of NAbs.
openaire   +3 more sources

Perspectives on the neutralization of interferons by antibody

Neurology, 2003
Interferon (IFN) neutralizing antibody (NAb) interferes with the binding of the IFN molecule to its cellular receptor, thereby preventing receptor activation required to trigger the cascade of signal transduction events that lead to the varied actions of IFN.
openaire   +3 more sources

Neutralization by Fragments of Antibody

1993
Experiments to determine whether or not the whole antibody molecule is necessary for neutralization were made possible by digestion with the proteolytic enzymes pepsin, which releases the Fc region leaving an F(ab)2 structure, or papain, which results in a monovalent antigen-binding fragment (Fab). Most data relate to IgG.
openaire   +2 more sources

Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies

Nature Network Boston, 2021
D. Planas, T. Bruel, L. Grzelak, F. Guivel-Benhassine, I. Staropoli, F. Porrot, C. Planchais, Julian Buchrieser, M. M. Rajah, Elodie Bishop, M. Albert, F. Donati, M. Prot, S. Behillil, V. Enouf, M. Maquart, M. Smati-lafarge, E. Varon, F. Schortgen, Layla Yahyaoui, Maria Gonzalez, J. de Seze, H. Péré, D. Veyer, A. Sève, E. Simon-Lorière, S. Fafi-Kremer, K. Stéfic, H. Mouquet, L. Hocqueloux, S. van der Werf, T. Prazuck, O. Schwartz   +32 more
semanticscholar   +1 more source

Zika-neutralizing antibodies [PDF]

Nature Immunology, 2017
openaire   +2 more sources

Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

Nature, 2021
Florian A. Lempp, Leah B. Soriaga, Martin Montiel-Ruiz, F. Benigni, Julia Noack, Young-Jun Park, S. Bianchi, A. Walls, John E. Bowen, Jiayi Zhou, Hannah Kaiser, Anshu Joshi, Maria L. Agostini, M. Meury, E. Dellota, S. Jaconi, E. Cameroni, J. Martinez-Picado, J. Vergara-Alert, N. Izquierdo-Useros, H. Virgin, A. Lanzavecchia, D. Veesler, L. Purcell, A. Telenti, D. Corti   +25 more
semanticscholar   +1 more source

HIV-Specific Neutralizing Antibodies

2001
Infection with human immunodeficiency virus type 1 (HIV-1) generates cellular and humoral immune responses of various magnitudes to multiple virus-specific antigens. Perhaps the most beneficial B cell response is one that is directed against the surface gp120 and transmembrane gp41 envelope glycoproteins of the virus; both glycoproteins are major ...
openaire   +2 more sources