Results 361 to 370 of about 1,883,437 (383)

Production of Neutralizing Antibody

Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa, Shuang, Liu
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Statistical issues in neutralizing antibodies

Neurology, 2003
Frequently the question of the effects of neutralizing antibodies (NAbs) is stated, but not clearly. Some ask: “Are we sure NAbs are important?” And others ask: “Are we sure NAbs are NOT important?” These two questions can lead to different statistical designs and different approaches to the investigation of the impact of NAbs.
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Perspectives on the neutralization of interferons by antibody

Neurology, 2003
Interferon (IFN) neutralizing antibody (NAb) interferes with the binding of the IFN molecule to its cellular receptor, thereby preventing receptor activation required to trigger the cascade of signal transduction events that lead to the varied actions of IFN.
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Testing for neutralizing antibodies

British Journal of Neuroscience Nursing, 2007
Interferon-beta drugs for multiple sclerosis sometimes give rise to immune proteins that neutralize their effects. Nicola O'Connell and Bronwen Roper look at testing for these neutralizing antibodies
Nicola O'Connell, Bronwen Roper
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Protective neutralizing antibodies

Science, 2020
Coronavirus Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Rogers et al.
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Interferon-β antibodies have a higher affinity in patients with neutralizing antibodies compared to patients with non-neutralizing antibodies

Journal of Neuroimmunology, 2006
In this study, we investigated the affinity, determined by a relative affinity assay, using increasing concentrations of sodium-isothiocyanate to disrupt the antigen antibody binding of neutralizing and non-neutralizing antibodies against interferon-beta (IFNbeta)-1a and -1b in 73 serum samples of MS patients treated with IFNbeta-1a or -1b.
C, Gneiss, P, Tripp, R, Ehling, M, Khalil, A, Lutterotti, R, Egg, I, Mayringer, B, Künz, T, Berger, M, Reindl, F, Deisenhammer   +10 more
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Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies

Nature Medicine, 2021
D. Planas, T. Bruel, L. Grzelak, F. Guivel-Benhassine, I. Staropoli, F. Porrot, C. Planchais, Julian Buchrieser, M. M. Rajah, Elodie Bishop, M. Albert, F. Donati, M. Prot, S. Behillil, V. Enouf, M. Maquart, M. Smati-lafarge, E. Varon, F. Schortgen, Layla Yahyaoui, Maria Gonzalez, J. de Seze, H. Péré, D. Veyer, A. Sève, E. Simon-Lorière, S. Fafi-Kremer, K. Stéfic, H. Mouquet, L. Hocqueloux, S. van der Werf, T. Prazuck, O. Schwartz   +32 more
semanticscholar   +1 more source

The Role of Antibody Bivalence in the Neutralization of Bacteriophage

The Journal of Immunology, 1967
Summary The neutralization of bacteriophage R 17 was studied with rabbit antibody induced by R 17 and several modified antibody preparations derived from the γG-immunoglobulin fraction of the antiserum. To assess the role of bivalence and the Fc fragment in the neutralization reaction both 7 S and 5 S monovalent and bivalent antibody ...
N R, Klinman, C A, Long, F, Karush
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Reexposure to Measles and the Neutralizing Antibody Titer

Archives of Pediatrics & Adolescent Medicine, 1962
Clinical measles is rarely diagnosed in an individual who has a history of previous infection. In a survey 1 of more than 1,000 pediatricians whose collective experience embraced many hundreds of thousands of patients, only 7 instances of second attacks of measles were disclosed.
S, KARELITZ, F S, MARKHAM, J M, RUEGSEGGER   +2 more
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Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

Nature, 2021
Florian A. Lempp, Leah B. Soriaga, Martin Montiel-Ruiz, F. Benigni, Julia Noack, Young-Jun Park, S. Bianchi, A. Walls, John E. Bowen, Jiayi Zhou, Hannah Kaiser, Anshu Joshi, Maria L. Agostini, M. Meury, E. Dellota, S. Jaconi, E. Cameroni, J. Martinez-Picado, J. Vergara-Alert, N. Izquierdo-Useros, H. Virgin, A. Lanzavecchia, D. Veesler, L. Purcell, A. Telenti, D. Corti   +25 more
semanticscholar   +1 more source