Results 1 to 10 of about 217,050 (318)
Kinetics of the neutralizing antibody response to respiratory syncytial virus infections in a birth cohort [PDF]
, 2013 The kinetics of respiratory syncytial virus (RSV) neutralizing antibodies following birth, primary and secondary infections are poorly defined. The aims of the study were to measure and compare neutralizing antibody responses at different time points in ...G.F. Medley, C.J. Sande, Sande, Charles J., P.A. Cane, Medley, Graham, Cane, Patricia, Nokes, D. James, Mutunga, M. N., M.N. Mutunga, E.A. Okiro, D.J. Nokes, Okiro, Emelda A. +11 morecore +1 more sourceLlama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules [PDF]
, 2011 For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (Schepens, B, Temperton, Nigel J., M. Koenders, C. Theo Verrips, Schillemans, J, Ibanez, Lorena Itatı, J. Melero, de Haard, HJ, Verrips, C. Theo, S. Van Gucht, C.T. Verrips, Michael Saunders, Bert Schepens, Temperton, Nigel J, Ibanez, Lorena, Koenders, M, Melero, Jose A., Schepens Bert, de Haard, Hans J, Vanlandschoot, P, Steven Van Gucht, Gonzalez-Pajuelo Maria, Van Gucht, S, Xavier Saelens, Vanlandschoot Peter, Anna Hultberg, B. Schepens, Gonzalez-Pajuelo, Maria, Schillemans Joris, Koenders, Mireille, Nigel J. Temperton, Saunders Michael, Melero José A., de Haard, Hans J., Schillemans, Joris, Ibañez Lorena Itatí, de Haard Hans J., Temperton Nigel J., Ibañez,, Lorena Itatí, H.J. de Haard, Robin A. Weiss, Hultberg, A, Schepens, Bert, C Theo Verrips, N.J. Temperton, Ibanez, LI, Van Gucht, Steven, Verrips, Theo, Maria Gonzalez-Pajuelo, L.I. Ibanez, Rosseels Valérie, José A Melero, Hans J de Haard, Mireille Koenders, Hultberg Anna, Weiss, RA, Saelens Xavier, Saunders, Michael, R.A. Weiss, Weiss Robin A., Saelens, Xavier, Hans J. de Haard, Lorena Itatí Ibañez, A. Hultberg, Gonzalez-Pajuelo, M, Weiss, Robin A., Saelens, X, Joris Schillemans, Verrips, CT, Peter Vanlandschoot, Van Gucht Steven, M. Saunders, Valérie Rosseels, V. Rosseels, Koenders Mireille, Robin A Weiss, P. Vanlandschoot, Rosseels, V, José A. Melero, Hultberg, Anna, M. Gonzalez-Pajuelo, Rosseels, Valerie, J. Schillemans, Ibañez, Lorena Itatí, Melero, Jose Antonio, Vanlandschoot, Peter, Weiss, Robin A, Saunders, M, Nigel J Temperton, X. Saelens, Melero, José A, Verrips C. Theo, Temperton, NJ, Melero, JA, Verrips, C Theo +94 morecore +1 more sourceVirus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis [PDF]
, 2001 Neutralizing antibodies represent a major host defense mechanism against viral infections. In mammals, passive immunity is provided by neutralizing antibodies passed to the offspring via the placenta or the milk as immunoglobulin G and secreted ...Pewe, L, John Webster, Whitelaw, C B, Andreas F. Kolb, Perlman, S, Siddell, S G, Stanley Perlman, C. Bruce A. Whitelaw, Stuart G. Siddell, Webster, J, Kolb, A F, Lecia Pewe +11 morecore +1 more sourceHepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes [PDF]
, 2009 Anti-hepatitis C virus (HCV) cross-neutralizing human monoclonal antibodies, directed against conserved epitopes on surface E2 glycoprotein, are central tools for understanding virus-host interplay, and for planning strategies for prevention and ...Patel, Ah, Ball Jonathan K., Nicasio Mancini, Nicola Clementi, Sautto, G, Clementi, N., Ball, J.K., Diotti, R.A., Burioni, R., Mario Perotti, Arvind H Patel, Nitti Giovanni, Diotti, Ra, Clementi Massimo, CLEMENTI, NICOLA, BURIONI, ROBERTO, Sautto, G., CLEMENTI, MASSIMO, Perotti, M., Jonathan K Ball, Massimo Clementi, Nitti, G, Giovanni Nitti, Patel, A.H., Clementi, M., Perotti Mario, Ball, Jk, Perotti, M, Patel Arvind H., Roberta A Diotti, Giuseppe Sautto, Mancini Nicasio, Diotti Roberta A., Mancini, N., Roberto Burioni, Sautto Giuseppe, MANCINI, NICASIO, Clementi Nicola, Burioni Roberto, Nitti, G. +39 morecore +1 more sourceCharacterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]
, 2014 The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb)
capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment
which will be too expensive to be accessible by the most ...Katja Klein, Julian K‐C. Ma, Klein, K, Ma, JK-C, Teh, AY, Ma, Julian K.C., Maresch, Daniel, Teh, AY-H, Klein, Katja, Ma, JK, Teh, Audrey Y.H., Audrey Y‐H. Teh, Daniel Maresch, Maresch, D +13 morecore +1 more sourceIn Vivo Emergence of HIV-1 Highly Sensitive to Neutralizing Antibodies [PDF]
, 2011 Background: The rapid and continual viral escape from neutralizing antibodies is well documented in HIV-1 infection. Here we report in vivo emergence of viruses with heightened sensitivity to neutralizing antibodies, sometimes paralleling the development O'Farrell Stephen, Pellegrino, P, Williams Ian, Williams, IG, Kelly M Cheney, Áine McKnight, Anna Forsman, Cheney, Kelly M, McKnight, Áine, Cheney Kelly M., Hué, Stéphane, Forsman Anna, Marlén M I Aasa-Chapman, McKnight, A, Marlén M. I. Aasa-Chapman, Ian Williams, Aasa-Chapman, Marlén MI, Cheney, KM, O'Farrell, S, Stéphane Hué, Kelly M. Cheney, Pellegrino, Pierre, Stephen O'Farrell, Forsman, A, O'Farrell, Stephen, Pierre Pellegrino, Williams, Ian, Forsman, Anna, Aasa-Chapman Marlén M. I., Aasa-Chapman, MMI, Hué Stéphane, McKnight Áine, Pellegrino Pierre, Williams, I, Hue, S, Aasa-Chapman, MM +35 morecore +1 more sourceMultiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies [PDF]
, 2014 The increased number of outbreaks of H5 and H7 LPAI and HPAI viruses in poultry has major public and animal health implications. The continuous rapid evolution of these subtypes and the emergence of new variants influence the ability to undertake ...Rafat Rahman (16267478), Calogero Terregino, Temperton, Nigel J., Giovanni Cattoli, Calogero Terregino (4163389), Cattoli, Giovanni, Nigel J. Temperton, Eleonora Molesti, Giovanni Cattoli (52822), Terregino, Calogero, Nigel J Temperton (16261166), Rahman, R., Rafat Rahman, Eleonora Molesti (686215), Temperton, N.J., Rahman, Rafat, Edward Wright, Wright, Edward, Molesti, E., Wright, E., Edward Wright (4468198), Molesti, Eleonora, Terregino, C., Cattoli, G. +23 morecore +1 more sourceA gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition [PDF]
, 2013 The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodies ...Ramos, Alejandra, Alexandre M. J. J. Bonvin (18079), David Lutje Hulsik, Verrips, C. Theo, Ying-ying Liu, Mccoy, Laura E, Liu, Ying-ying, Battella, Simone, Jean-Pierre Simorre, C. Theo Verrips (200972), Miriam Hock, Miriam Hock (386536), Lucy Rutten (386540), Nika M. Strokappe (386532), Davis, David, Hinz, Andreas, Alejandra Ramos, Mohamed El Khattabi (386534), Bonvin, Alexandre M. J. J., Michael S Seaman, Rutten, Lucy, Alexandre M J J Bonvin, Simone Battella, Marlén M. I. Aasa-Chapman (208291), Pascal Poignard (244468), Sabin, Charles, Pascal Poignard, Seaman, Michael S., Anna Forsman Quigley, Pauline Macheboeuf, Seaman, Michael, Andreas Hinz (237046), Forsman Quigley, Anna, Anna Forsman Quigley (177474), Strokappe, Nika M, C Theo Verrips, Simorre, Jean-Pierre, Mohamed El Khattabi, Hulsik, David Lutje, Andreas Hinz, Winfried Weissenhorn (214542), McCoy, Laura E., Langedijk, Johannes P M, Johannes P. M. Langedijk (254439), Pauline Macheboeuf (386537), Charles Sabin, Marlén M I Aasa-Chapman, David Davis (190113), Robin A. Weiss (254468), Johannes P M Langedijk, Favier, Adrien, Lucy Rutten, Laura E. McCoy (386535), Adrien Favier (386539), Hock, Miriam, Alejandra Ramos (386538), Weiss, Robin A., Nika M Strokappe, David Lutje Hulsik (177480), Winfried Weissenhorn, Macheboeuf, Pauline, Lutje Hulsik, David, David Davis, Robin A Weiss, Aasa-Chapman, Marlén M. I., Strokappe, Nika M., Ying-ying Liu (386531), Weissenhorn, Winfried, Adrien Favier, Weiss, Robin A, Simone Battella (386533), Langedijk, Johannes P. M., Bonvin, Alexandre M J J, Michael S. Seaman (155998), Jean-Pierre Simorre (177519), El Khattabi, Mohamed, Seaman, Michael S, Aasa-Chapman, Marlén M I, Laura E McCoy, Poignard, Pascal, Verrips, C Theo, Charles Sabin (75940) +81 morecore +1 more source