Results 91 to 100 of about 217,050 (318)

JE-ADVAX Vaccine Protection against Japanese Encephalitis Virus Mediated by Memory B Cells in the Absence of CD8⁺T Cells and Pre-Exposure Neutralizing Antibody [PDF]

, 2013
Maximilian Larena, Natalie A. Prow, Roy A. Hall, Nikolai Petrovsky, Mario Lobigs   +4 more
openalex   +1 more source

Genetic and immunological characterization of new subtype G envelope expressing HIV-1 pseudoviruses

, 2014
Includes bibliographical references.One of the greatest challenges for the development of an effective HIV-1 vaccine is the high genetic diversity of this pathogen and the complex escape mechanisms employed by the envelope gp120 and gp41 glycoprotein ...
Essomba, Rene Ghislain
core  

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

HETEROGENEITY IN LEVELS OF SERUM NEUTRALIZING ANTIBODIES AGAINST VIRAL HEMORRHAGIC SEPTICEMIA VIRUS GENOTYPE IVB AMONG FISH SPECIES IN LAKE ST. CLAIR, MICHIGAN, USA [PDF]

, 2012
Elena V. Millard, Mohamed Faisal
openalex   +1 more source

Tracing HIV-1 strains that imprint broadly neutralizing antibody responses.

, 2018
Understanding the determinants of broadly neutralizing antibody (bNAb) evolution is crucial for the development of bNAb-based HIV vaccines. Despite emerging information on cofactors that promote bNAb evolution in natural HIV-1 infections, in which the ...
Battegay, Manuel, Yerly, Sabine, Rusert, Peter, Roger D. Kouyos, Kuster, Herbert, Peter Rusert, Schanz, Merle, Alex Marzel, Jürg Böni, Calmy, Alexandra, Weber, Jacqueline, Liechti, Thomas, Braun, Dominique L, Dominique L. Braun, Swiss HIV Cohort Study, Merle Schanz, Günthard, Huldrych F., Metzner, Karin J, Andri Rauch, Hanna Ebner, Klimkait, Thomas, Alexandra Calmy, Uhr, Therese, Aubert, Vincent, Scherrer, Alexandra U, Christine Leemann, Jean-Philippe Chave, Leemann, Christine, Yerly Ferrillo, Sabine, Huber, Michael, Jacqueline Weber, Marzel, Alex, Günthard, Huldrych F, Enos Bernasconi, Alexandra U. Scherrer, Kouyos, Roger D., Hoffmann, Matthias, Therese Uhr, Scherrer, Alexandra U., Matthias Hoffmann, Baumann, Nicolas S, Michael Huber, Böni, Jürg, Trkola, Alexandra, Thomas Klimkait, Bernasconi, Enos, Kadelka, Claus, Herbert Kuster, Huldrych F. Günthard, Ebner, Hanna, Alexandra Trkola, Claus Kadelka, Kouyos, Roger D, Braun, Dominique L., Thomas Liechti, Nicolas S. Baumann, Nikolas Friedrich, Sabine Yerly, Rauch, Andri, Karin J. Metzner, Manuel Battegay, Chave, Jean-Philippe, Friedrich, Nikolas, Metzner, Karin J., Vincent Aubert, Baumann, Nicolas S., Cavassini, Matthias, Matthias Cavassini   +67 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction [PDF]

, 2020
Chee Wah Tan, Wan Ni Chia, Xijian Qin, Pei Liu, Mark Chen, Charles Kevin Tiu, Zhiliang Hu, Vivian Chih-Wei Chen, Barnaby Edward Young, Wan Rong Sia, Yee‐Joo Tan, Randy Foo, Yongxiang Yi, David Chien Lye, Danielle E. Anderson, Lin‐Fa Wang   +15 more
openalex   +1 more source

COVID‐19: are neutralizing antibodies neutralizing enough? [PDF]

Transfusion, 2020
openaire   +2 more sources

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Molecular analysis of a public cross-neutralizing antibody response to SARS-CoV-2

, 2022
Meng Yuan, Yiquan Wang, Huibin Lv, Timothy J.C. Tan, Ian A. Wilson, Nicholas C. Wu   +5 more
openalex   +1 more source