Results 131 to 140 of about 207,642 (318)

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Neutralizing antibodies in convalescent patients [PDF]

Nature Reviews Immunology, 2020
Uhl, LFK, Chauveau, A
openaire   +3 more sources

A Reproducible and Scalable Process for High Yield Mesenchymal Stromal Cell Extracellular Vesicles Production

Advanced Materials Technologies, EarlyView.
Mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) are a promising therapeutic tool for regenerative medicine. However, the field lacks a reproducible high‐yield production method to answer the quantities needed for clinical translation.
Christophe Wong, Elise Madec, Jeanne Volatron, Max Piffoux, Amanda K. A. Silva, Florence Gazeau, Jean‐Philippe Herbeuval, Thibaut Fourniols   +7 more
wiley   +1 more source

Visualization of immune pathways that enhance the neutralizing antibody response to vaccines after primary immunization

mBio
We examined the relationship between the association of a vaccine antigen with immune cells in secondary lymphoid organs shortly after immunization and the resulting neutralizing antibody response induced by that antigen using three antigenic forms of ...
Anita Verma, Roberto De Pascalis, Christopher P. Mocca, Xiaohong Li, Drusilla L. Burns   +4 more
doaj   +1 more source

Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection

, 2005
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aubin, K., Williams, I., Jones, N.A., Borrow, P., Holuigue, S., Cornforth, D., Wong, M., Pellegrino, P., McKnight, A., Aasa-Chapman, M.M.I., Newton, P.   +10 more
core  

Characterisation of llama antibody fragments able to act as HIV-1 entry inhibitors [PDF]

, 2009
Human immunodeficiency virus type 1 (HIV-1) entry into cells is mediated by the functional envelope spike, which consists of trimers of gp120 bound to gp41.
Forsman, A M M, Forsman, A.M.M.
core  

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Genetic and immunological characterization of new subtype G envelope expressing HIV-1 pseudoviruses

, 2014
Includes bibliographical references.One of the greatest challenges for the development of an effective HIV-1 vaccine is the high genetic diversity of this pathogen and the complex escape mechanisms employed by the envelope gp120 and gp41 glycoprotein ...
Essomba, Rene Ghislain
core  

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Tracing HIV-1 strains that imprint broadly neutralizing antibody responses.

, 2018
Understanding the determinants of broadly neutralizing antibody (bNAb) evolution is crucial for the development of bNAb-based HIV vaccines. Despite emerging information on cofactors that promote bNAb evolution in natural HIV-1 infections, in which the ...
Battegay, Manuel, Yerly, Sabine, Rusert, Peter, Roger D. Kouyos, Kuster, Herbert, Peter Rusert, Schanz, Merle, Alex Marzel, Jürg Böni, Calmy, Alexandra, Weber, Jacqueline, Liechti, Thomas, Braun, Dominique L, Dominique L. Braun, Swiss HIV Cohort Study, Merle Schanz, Günthard, Huldrych F., Metzner, Karin J, Andri Rauch, Hanna Ebner, Klimkait, Thomas, Alexandra Calmy, Uhr, Therese, Aubert, Vincent, Scherrer, Alexandra U, Christine Leemann, Jean-Philippe Chave, Leemann, Christine, Yerly Ferrillo, Sabine, Huber, Michael, Jacqueline Weber, Marzel, Alex, Günthard, Huldrych F, Enos Bernasconi, Alexandra U. Scherrer, Kouyos, Roger D., Hoffmann, Matthias, Therese Uhr, Scherrer, Alexandra U., Matthias Hoffmann, Baumann, Nicolas S, Michael Huber, Böni, Jürg, Trkola, Alexandra, Thomas Klimkait, Bernasconi, Enos, Kadelka, Claus, Herbert Kuster, Huldrych F. Günthard, Ebner, Hanna, Alexandra Trkola, Claus Kadelka, Kouyos, Roger D, Braun, Dominique L., Thomas Liechti, Nicolas S. Baumann, Nikolas Friedrich, Sabine Yerly, Rauch, Andri, Karin J. Metzner, Manuel Battegay, Chave, Jean-Philippe, Friedrich, Nikolas, Metzner, Karin J., Vincent Aubert, Baumann, Nicolas S., Cavassini, Matthias, Matthias Cavassini   +67 more
core   +1 more source