Results 161 to 170 of about 280,630 (308)

RETRACTION: Antiresistin Neutralizing Antibody Alleviates Doxorubicin-Induced Cardiac Injury in Mice. [PDF]

Dis Markers
Markers D.
europepmc   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Immunoglobulin G and neutralizing antibody response after CoronaVac. [PDF]

Rev Assoc Med Bras (1992)
Assis PBC, Ferreira LN, Magalhães FMV, Távora PF, Santos LID.   +4 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Protective Human Papillomavirus Type 16/18 Vaccine-Induced Neutralizing Antibody Levels Remain Elusive. [PDF]

Open Forum Infect Dis
Lehtinen M, Eriksson T, Petäjä T, Harjula K, Heikkilä K, Hokkanen M, Butt J, Michels B, Sehr P, Müller M, Pimenoff V, Waterboer T.   +11 more
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Seroprevalence of measles-specific IgG and genotype-specific neutralizing antibody responses in clinically confirmed cases during the 2021–2023 measles outbreaks in Liberia [PDF]

Res Sq
Donzo KS, Logan N, MOON TD, Jetoh RW, Hosie MJ, Quashie PK, Willett BJ, Kusi KA.   +7 more
europepmc   +2 more sources

A potent Gc neutralizing antibody reveals architecture-dependent bispecific protection against SFTSV. [PDF]

Emerg Microbes Infect
Lu H, Li L, Zhang N, Liu Y, Liu B, Sun Y, Zhang J, Liu S, Luo J, Liao J, Lv K, Yue X, Xu M, Zhao J, Wu X, Chen X, Tao C, Guo Y, Zhang Z, Wang M, Chen YQ.   +20 more
europepmc   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Does the Chimerization Process Affect the Immunochemical Properties of WNV-Neutralizing Antibody 900? [PDF]

Int J Mol Sci
Isaeva AA, Nesmeyanova VS, Shanshin DV, Ushkalenko ND, Volosnikova EA, Esina TI, Protopopova EV, Svyatchenko VA, Loktev VB, Olkin SE, Danilenko ED, Kazachinskaia EI, Shcherbakov DN.   +12 more
europepmc   +1 more source