Results 131 to 140 of about 220,141 (335)
Abstract Objectives Methotrexate (MTX) is frequently prescribed in paediatric inflammatory bowel disease (IBD), with routine laboratory monitoring to detect adverse events (AEs), such as hepatotoxicity and myelotoxicity. However, data on the incidence and predictors of these AEs remain limited.
Eva Vermeer +7 more
wiley +1 more source
Expansion of a unique subpopulation of cytotoxic T cells that express a C alpha V delta 1 T-cell receptor gene in a patient with severe persistent neutropenia [PDF]
Ilan Bank +7 more
openalex +1 more source
ABSTRACT Background and Objective Palliative surgery in oncology aims to relieve symptoms, improve quality of life, and respect patient autonomy in advanced cancer. This study aimed to develop evidence‐based recommendations for safely indicating and performing palliative surgeries in Brazil, considering clinical, ethical, and multidisciplinary aspects.
Audrey Cabral Ferreira de Oliveira +15 more
wiley +1 more source
Extended Infusions of Meropenem for Febrile Neutropenia [PDF]
Background: Neutropenic fever is an oncologic emergency that requires quick intervention with anti-pseudomonal beta-lactam antibiotics, such as meropenem.
Przybylski, PharmD, Daniel J +1 more
core +1 more source
Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat
ABSTRACT Mpox is a zoonotic viral infection caused by monkeypox virus (MPXV) and risk factors for its dissemination include previous dermatoses such as atopic dermatitis [1]. We present the case of a 30‐year‐old male with an unusual and extensive presentation of mpox following unprotected sexual intercourse, with an excellent response to tecovirimat ...
Andrés Vidal González +6 more
wiley +1 more source
Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment [PDF]
A Rai +30 more
core +3 more sources
Evaluating the indotecan–neutropenia relationship in patients with solid tumors by population pharmacokinetic modeling and sigmoidal Emax regressions [PDF]
Jan H. Beumer +11 more
openalex +1 more source
Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley +1 more source

