Results 141 to 150 of about 220,141 (335)

Association between neutropenia and efficacy in patients with refractory mCRC receiving trifluridine/tipiracil + bevacizumab: post hoc analysis of the SUNLIGHT trial

open access: yesESMO Gastrointestinal Oncology
Background: The efficacy of trifluridine/tipiracil (FTD/TPI) + bevacizumab compared with FTD/TPI for the treatment of refractory metastatic colorectal cancer (mCRC) was demonstrated in the SUNLIGHT trial.
G.W. Prager   +8 more
doaj   +1 more source

Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis: systematic review and mixed method treatment comparison [PDF]

open access: yes
Background This study assesses the efficacy of three granulocyte colony-stimulating factors (G-CSFs; pegfilgrastim, filgrastim and lenograstim) in preventing febrile neutropenia (FN). Methods A systematic review was undertaken.
Akehurst, R.   +4 more
core  

Reducing inappropriate antibiotic use in febrile neutropenia in hematology patients through the implementation of an antibiotic de-escalation protocol [PDF]

open access: hybrid
Jinghao Nicholas Ngiam   +8 more
openalex   +1 more source

A Single Center Survey of Patients With Congenital Neutropenia: Report From Northwestern Iran

open access: yesActa Medica Iranica, 2018
Neutropenia is characterized by a decrease in circulating neutrophil counts and consequent infections.  The present study was performed so as to describe the clinical and laboratory findings of patients with congenital neutropenia in northwestern Iran ...
Mahnaz Sadeghi-Shabestari   +4 more
doaj  

Exploring Immune-Related Adverse Events: A Case of Febrile Neutropenia in a Melanoma Patient Receiving Immunotherapy

open access: yesCase Reports in Oncology
Introduction: The introduction of immune checkpoint inhibitors (ICIs) has opened a new chapter in cancer treatment. Nevertheless, their use may result in immune-related adverse events (irAEs) with multifactorial determinants, complex mechanisms, and ...
Melina Yerolatsite   +6 more
doaj   +1 more source

Oncologic Outcomes of Transoral Robotic Surgery in HPV‐Associated OPSCC: A Systematic Review and Meta‐Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To define survival and recurrence outcomes of HPV associated oropharyngeal squamous cell carcinoma (OPSCC) following transoral robotic surgery (TORS). Data Sources PubMed, Scopus, CINAHL. Review Methods A systematic review and meta‐analysis were performed on studies employing TORS in HPV‐associated OPSCC.
Matthew H. Cheung   +6 more
wiley   +1 more source

Antibiotic‐associated neutropenia is marked by the depletion of intestinal Lachnospiraceae and associated metabolites in pediatric patients

open access: yesHemaSphere
Prolonged antibiotic exposure causes dangerous hematologic side effects, including neutropenia, in up to 34% of patients. Murine studies established a link between the intestinal microbiota and hematopoiesis.
Josaura Fernandez‐Sanchez   +12 more
doaj   +1 more source

HAX1 mutation in an infant with severe congenital neutropenia

open access: yesThe Turkish Journal of Pediatrics, 2010
Severe congenital neutropenia (SCN) is a rare primary myelopoiesis disorder, characterized by persistent severe neutropenia and early-onset bacterial infections.
Aziz Eghbali   +4 more
doaj  

Neutropenia febril en pacientes oncológicos pediátricos

open access: hybrid, 2021
Elsa Lissette Hernández Negrete   +3 more
openalex   +2 more sources

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar   +8 more
wiley   +1 more source

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