Results 221 to 230 of about 140,144 (311)
MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley +1 more source
Rare Invasive Fusarium Sinusitis in a Transiently Immunosuppressed Patient. [PDF]
Archibald VL +4 more
europepmc +1 more source
The flow of this trial and the treatment schedule of adjuvant chemotherapy with nedaplatin plus docetaxel for completely resected non‐small cell lung cancer (NSCLC) (A). The primary endpoint of this study was tolerability, assessed by the completion rate of the planned four chemotherapy cycles. As a result, it was 74.3%, exceeding that reported for the
Koji Teramoto +9 more
wiley +1 more source
Clinical Applications of CDK4/6 Inhibitors in HR+/HER2, and Personalized Treatment Strategies: A Narrative Review. [PDF]
Zhong G, Yang T, Lin S, Zhong M.
europepmc +1 more source
Retreatment with talquetamab and pomalidomide in triple‐class–BCMA–GPRC5D refractory myeloma
British Journal of Haematology, EarlyView.
Kian J. Rahbari +4 more
wiley +1 more source
Autoimmune myelofibrosis with a <i>TLR8</i> gain-of-function defect. [PDF]
Qu S +5 more
europepmc +1 more source

