Evolving treatments for Sjögren disease: current approaches and emerging targets
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani +3 more
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Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia. [PDF]
Wang Z, Jing H, Chen Y, Zhong L, Yang J.
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Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar +16 more
wiley +1 more source
Relaxation of Japan's clozapine monitoring system is urgently needed: Adding 10,000 future prescriptions may prevent up to 400 schizophrenia-related suicides and cost 1 death by agranulocytosis. [PDF]
de Leon J, Kikuchi Y, Yasui-Furukori N.
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A phase 1 study of R-GDP-venetoclax before autologous transplant in relapsed/refractory large B-cell lymphoma (CCTG LY.18). [PDF]
Assouline S +16 more
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Case Report: Immunotherapy-induced Felty syndrome in a patient with metastatic melanoma. [PDF]
Park LS +5 more
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NFE2L2 rs35652124C>T polymorphism predicts Grade 4 neutropenia in esophageal cancer patients treated with docetaxel, cisplatin, and fluorouracil chemotherapy: results from exploratory and validation cohorts. [PDF]
Nomura H +4 more
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Sacituzumab govitecan in patients with metastatic breast cancer: pooled safety analysis of data from patients in North America, Europe, and Asia. [PDF]
Rugo HS +12 more
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Association Between a Shortage of Normal Saline and In-Hospital Outcomes Among Individuals With Febrile Neutropenia. [PDF]
Stacks AE, Russell LA, Weeda ER.
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