Results 311 to 320 of about 274,076 (393)

KEYNOTE‐A17: First‐Line Pembrolizumab Plus Cisplatin–Pemetrexed in Japanese Participants With Advanced Pleural Mesothelioma

open access: yesCancer Science, EarlyView.
In the phase 1b KEYNOTE‐A17 study of first‐line pembrolizumab plus chemotherapy in Japanese participants with advanced pleural mesothelioma (PM), 2 of 18 participants (11%) evaluated experienced dose‐limiting toxicities. The objective response rate among all 19 participants in the study was 74%, with 14 participants achieving a partial response and a ...
Takashi Kijima   +11 more
wiley   +1 more source

Phase III Clinical Trial of KRN8601 (rhG-CSF) for Neutropenia in Patients with Human Immunodeficiency Virus Infection

open access: bronze, 1994
Satoshi Kimura   +16 more
openalex   +2 more sources

Real‐world outcomes of vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome at a tertiary referral centre

open access: yes
British Journal of Haematology, EarlyView.
Lucia Lee   +15 more
wiley   +1 more source

Pyrotinib and Nab‐Paclitaxel in HER2‐Positive Breast Cancer (PANHER Trial): A Prospective, Single‐Arm, Phase II Trial

open access: yesCancer Science, EarlyView.
In this multicenter, single‐arm, open‐label phase II trial, patients with HER2‐positive breast cancer who had previously received chemotherapy with taxanes or anthracyclines were enrolled to receive pyrotinib combined with nab‐paclitaxel, and the results demonstrated promising efficacy with an acceptable safety profile.
Huan Li   +23 more
wiley   +1 more source

Parallel Toxicities: A Comparative Analysis of Chemotherapy-Induced Neutropenia and Alopecia. [PDF]

open access: yesCancers (Basel)
Gaumond SI   +5 more
europepmc   +1 more source

The C11orf24 Gene as a Useful Biomarker for Predicting Severe Neutropenia in Modified FOLFIRINOX for Pancreatic Cancer

open access: yesCancer Science, EarlyView.
FOLFIRINOX improves the prognosis of patients with pancreatic cancer; however, despite UGT1A1 screening, adverse events, such as severe neutropenia, occur frequently. The diagnostic performance of the neutropenia prediction model showed areas under the curve of 0.754 (sensitivity=0.605, specificity=0.848) and 0.856 (sensitivity=0.800, specificity=0.893)
Gen Kanesada   +9 more
wiley   +1 more source

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