Results 331 to 340 of about 274,076 (393)

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

European Journal of Haematology, EarlyView.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski, Claudia Schmoor, Tobias Berg, Usama‐Ur Rehman, Marcus Schittenhelm, Katharina Götze, Andrea Kündgen, Caroline Pabst, Tobias Ma, Anna Frey, Julia Stomper, Dietmar Pfeifer, Eric Metzger, Johannes Jung, Kevin Moschallski, Johanna Thomas, Gesine Bug, Justus Duyster, Manfred Jung, Roland Schüle, Ralph Wäsch, Olga Grishina, Michael Lübbert   +22 more
wiley   +1 more source

Progress of antibody-drug conjugates in the treatment of locally advanced or metastatic urothelial carcinoma: opportunities and challenges. [PDF]

Discov Oncol
Zeng F, Han Q, Ding T, Tian C, Jiang M.
europepmc   +1 more source

Efficacy and Safety of Bendamustine‐Rituximab for Nodular Lymphocyte Predominant Hodgkin Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Bendamustine‐rituximab (BR) has demonstrated efficacy and tolerability in the treatment of various indolent B‐cell lymphomas, but there is limited data regarding its outcomes in nodular lymphocyte predominant B‐cell (Hodgkin) lymphoma (NLPBL).
Alexander Robin, Carolyn Owen, Sarah Perry, Lesley Street, Neil Chua, Douglas Stewart, Robert Puckrin   +6 more
wiley   +1 more source

Prognostic Value of Serum and Bronchoalveolar Lavage Fluid Galactomannan Levels in Invasive Aspergillosis: An 8-Year Experience at a Tertiary Cancer Center. [PDF]

J Fungi (Basel)
Wehbe S, Chaftari AM, Hachem R, Dagher H, Haddad A, Philip A, Jiang Y, Zakhour R, Bakht P, Shrestha J, Lamie P, Sherchan R, Makhoul J, Chaftari P, Raad II.   +14 more
europepmc   +1 more source

Neutropenia management

Annals of Oncology, 2006
openaire   +2 more sources

Diagnostic approach to chronic diarrhoea in adult horses

Equine Veterinary Education, Volume 37, Issue 6, Page 328-336, June 2025.
Summary Chronic diarrhoea presents a diagnostic challenge for both human physicians and equine veterinarians. There is currently no consensus in the equine veterinary literature on the definition of chronic diarrhoea. The differential list is extensive and identifying diarrhoea by pathophysiologic mechanism can help remove less likely diagnoses ...
E. Sjolin, A. Lack, L. G. Arroyo
wiley   +1 more source

Telpegfilgrastim for chemotherapy-induced neutropenia in patients with non-small cell lung cancer: a multicentre, randomized, phase 3 study. [PDF]

BMC Cancer
Shi Y, Wang X, Pei Z, Shi H, Zhang Y, Yi T, Mei J, Guo Y, Dong Y, Ma T, Zhang Q, Jia X, Zhu Z, Xu S, Liu Y, Niu H, Jiang W, Jiang X, Zhou S, Sun L.   +19 more
europepmc   +1 more source

Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023

Equine Veterinary Journal, EarlyView.
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock, Melissa S. Aprea, Manigandan Lejeune, Joy E. Tomlinson   +3 more
wiley   +1 more source