Results 361 to 370 of about 274,076 (393)
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Supportive Care in Cancer, 1993
Severe neutropenia and its related infectious complications remain a permanent threat for patients receiving intensive chemotherapy, especially in the context of bone marrow transplantation. Chemoprophylaxis and use of colony-stimulating factors have altered the severity of the clinical picture in a favorable direction: neutropenia can be shortened ...
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Severe neutropenia and its related infectious complications remain a permanent threat for patients receiving intensive chemotherapy, especially in the context of bone marrow transplantation. Chemoprophylaxis and use of colony-stimulating factors have altered the severity of the clinical picture in a favorable direction: neutropenia can be shortened ...
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Hematology, 2009
Abstract Congenital neutropenia comprises a variety of genetically heterogeneous phenotypic traits. Molecular elucidation of the underlying genetic defects has yielded important insights into the physiology of neutrophil differentiation and function.
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Abstract Congenital neutropenia comprises a variety of genetically heterogeneous phenotypic traits. Molecular elucidation of the underlying genetic defects has yielded important insights into the physiology of neutrophil differentiation and function.
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New England Journal of Medicine, 1975
Serologic tests for antineutrophil antibodies were used to determine if autoantibodies cause neutropenia. The serums of five patients with idiopathic neutropeniaopsonized normal neutrophils, causing them to be ingested by rabbit macrophages or else to activate glucose oxidation rates of other normal neutrophils by at least twice the rate of controls ...
L A, Boxer +3 more
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Serologic tests for antineutrophil antibodies were used to determine if autoantibodies cause neutropenia. The serums of five patients with idiopathic neutropeniaopsonized normal neutrophils, causing them to be ingested by rabbit macrophages or else to activate glucose oxidation rates of other normal neutrophils by at least twice the rate of controls ...
L A, Boxer +3 more
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Vox Sanguinis, 1984
In 1926, Charles Doan observed that sera from some patients agglutinated leukocytes from other individuals. This was the beginning of modern leukocyte immunology. The first report on autoimmune leucopenia was that of Francke, who attributed the disorder to the “leukolysine” he found in a patient’s serum.
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In 1926, Charles Doan observed that sera from some patients agglutinated leukocytes from other individuals. This was the beginning of modern leukocyte immunology. The first report on autoimmune leucopenia was that of Francke, who attributed the disorder to the “leukolysine” he found in a patient’s serum.
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Pediatric Clinics of North America, 1980
Neutropenia can occur because of abnormalities of marrow stem cell development, poor release of polymorphonuclear leukocytes from the marrow reserve, or decreased survival of polymorphonuclear leukocytes. Some of the more important clinical entities are discussed.
R M, Weetman, L A, Boxer
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Neutropenia can occur because of abnormalities of marrow stem cell development, poor release of polymorphonuclear leukocytes from the marrow reserve, or decreased survival of polymorphonuclear leukocytes. Some of the more important clinical entities are discussed.
R M, Weetman, L A, Boxer
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Annals of Internal Medicine, 1986
Excerpt To the editor: In the September issue, Wallis and colleagues (1) describe the association of polyarthritis and neutropenia associated with circulating large granular lymphocytes.
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Excerpt To the editor: In the September issue, Wallis and colleagues (1) describe the association of polyarthritis and neutropenia associated with circulating large granular lymphocytes.
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Therapeutic Drug Monitoring, 2016
Background: Vancomycin (VCM) dosage optimization in the early stages of therapy is required to achieve target trough serum concentrations, particularly in critically ill patients.
K. Hirai +6 more
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Background: Vancomycin (VCM) dosage optimization in the early stages of therapy is required to achieve target trough serum concentrations, particularly in critically ill patients.
K. Hirai +6 more
semanticscholar +1 more source
International Journal of Antimicrobial Agents, 2000
Newer treatment strategies for the management of febrile neutropenic patients are being developed. These include: (a) hospital based oral therapy; (b) early discharge after initial stabilization in-hospital, and (c) out-patient therapy. All strategies are likely to be more successful in patients with short-lived neutropenia (< or = 7 days) than in ...
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Newer treatment strategies for the management of febrile neutropenic patients are being developed. These include: (a) hospital based oral therapy; (b) early discharge after initial stabilization in-hospital, and (c) out-patient therapy. All strategies are likely to be more successful in patients with short-lived neutropenia (< or = 7 days) than in ...
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Annals of Internal Medicine, 1977
A patient with hyperthyroidism and severe neutropenia had a clinical course and family history that suggested an immune cause. Neutrophil-binding IgG was demonstrated in serum using the Fab-anti Fab assay. The antineutrophil factor bound specifically to either homologous or autologous neutrophils and could be adsorbed by the target neutrophils.
A L, Lightsey +5 more
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A patient with hyperthyroidism and severe neutropenia had a clinical course and family history that suggested an immune cause. Neutrophil-binding IgG was demonstrated in serum using the Fab-anti Fab assay. The antineutrophil factor bound specifically to either homologous or autologous neutrophils and could be adsorbed by the target neutrophils.
A L, Lightsey +5 more
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Journal of Clinical Psychiatry, 2016
OBJECTIVE To evaluate the epidemiology, pathobiology, and management of benign ethnic neutropenia and determine the extent to which these factors should influence measures designed to avoid clozapine-induced agranulocytosis.
P. Manu +4 more
semanticscholar +1 more source
OBJECTIVE To evaluate the epidemiology, pathobiology, and management of benign ethnic neutropenia and determine the extent to which these factors should influence measures designed to avoid clozapine-induced agranulocytosis.
P. Manu +4 more
semanticscholar +1 more source