Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management [PDF]
We assessed the impact on survival of angiogenesis and inflammation-related factors, particularly LDH serum levels, platelet, neutrophil and lymphocyte counts, and neutrophil-to-lymphocyte ratio (NLR), in metastatic colorectal cancer patients receiving ...
Aprile, G +12 more
core +2 more sources
Derived neutrophil lymphocyte ratio is predictive of survival from intermittent therapy in advanced colorectal cancer: a post hoc analysis of the MRC COIN study [PDF]
BACKGROUND: The phase III COntinuous or INtermittent (COIN) trial failed to show non-inferiority of intermittent compared with continuous chemotherapy for advanced colorectal cancer in overall survival (OS).
A Dirican +13 more
core +3 more sources
How and why systemic inflammation worsens quality of life in patients with advanced cancer [PDF]
Introduction: The presence of an innate host systemic inflammatory response has been reported to be a negative prognostic factor in a wide group of solid tumour types in both the operable and advanced setting, both local and distant.
Dolan, Ross D. +4 more
core +1 more source
Ebru Yuce1,2 1Department of Gynecology and Obstetrics, Yuksek Ihtisas University, Faculty of Medicine, Ankara, Turkey; 2Department of Gynecology and Obstetrics, Liv Hospital, Ankara, TurkeyCorrespondence: Ebru Yuce, Department of Gynecology and ...
Yuce E
doaj
Prognostic Significant of Neutrophil: Lymphocyte Ratio, Platelet – Lymphocyte ratio, and Lymphocyte – Monocyte ratio in Kurdish Patients with breast cancer [PDF]
Objective: The purpose of this study was to investigate the prognostic impact of neutrophil to lymphocyte ratio (NLR), derived neutrophil to lymphocyte ratio (dNLR), platelet to lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) on breast ...
S. Khazaei +3 more
doaj +1 more source
Mycobacterium tuberculosis Drives Expansion of Low-Density Neutrophils Equipped With Regulatory Activities [PDF]
In human tuberculosis (TB) neutrophils represent the most commonly infected phagocyte but their role in protection and pathology is highly contradictory.
La Manna, M. P. +8 more
core +1 more source
Yan Chen,* Shengyue Chen,* Yuanyuan Han, Qing Xu, Xin Zhao Department of Cardiology, the Second Hospital of Dalian Medical University, Dalian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Zhao ...
Chen Y, Chen S, Han Y, Xu Q, Zhao X
doaj
Background Psoriasis is a chronic immune‐mediated skin disorder. Systemic inflammation plays an important role in the pathogenesis of psoriasis. Methods A total of 477 patients with psoriasis vulgaris (PsV, n = 347), generalized pustular psoriasis (GPP ...
Wen-Ming Wang +5 more
doaj +1 more source
Platelet-to-lymphocyte ratio in the setting of liver transplantation for hepatocellular cancer. A systematic review and meta-analysis [PDF]
AIM: To perform a systematic review and meta-analysis on platelet-to-lymphocyte ratio (PLR) as a risk factor for post-transplant hepatocellular cancer (HCC) recurrence. METHODS: A systematic literature search was performed using PubMed.
Corradini, Stefano Ginanni +8 more
core +1 more source
Getnet Ayalew,1 Birhan Mulugeta,2 Yeabfekad Haimanot,3 Tiruneh Adane,4 Biruk Bayleyegn,4 Aberham Abere5 1Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar ...
Ayalew G +5 more
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