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The Neutrophil and Preeclampsia
Seminars in Reproductive Medicine, 1998Endothelial injury is common to all pathological features of preeclampsia. Neutrophil activation has been implicated in the pathophysiology of preeclampsia and requires binding and transmigration of neutrophils through the endothelium. This occurs via an interaction of endothelial adhesion molecules and surface receptors on neutrophils. Upon activation,
P Clark, F Boswell, I A Greer
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Current Allergy and Asthma Reports, 2007
Asthma is a complex disease with a significant inflammatory component. Multiple cell types are involved in its pathophysiology. The presence of eosinophils, the cell usually associated with allergic diseases, does not fully explain the inflammation found in asthma.
Ana L. MacDowell, Stephen P. Peters
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Asthma is a complex disease with a significant inflammatory component. Multiple cell types are involved in its pathophysiology. The presence of eosinophils, the cell usually associated with allergic diseases, does not fully explain the inflammation found in asthma.
Ana L. MacDowell, Stephen P. Peters
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Current Opinion in Hematology, 1996
Neutrophils are the most abundant leukocytes and serve as a first line of defense against infectious microorganisms. For this purpose, neutrophils contain granules filled with proteolytic and other cytotoxic enzymes. Neutrophils have the shortest lifespan of all leukocytes.
Dirk Roos, Christa H. E. Homburg
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Neutrophils are the most abundant leukocytes and serve as a first line of defense against infectious microorganisms. For this purpose, neutrophils contain granules filled with proteolytic and other cytotoxic enzymes. Neutrophils have the shortest lifespan of all leukocytes.
Dirk Roos, Christa H. E. Homburg
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Acta Haematologica, 2003
Regulation of the neutrophil life span by apoptosis provides a fine balance between their function as effector cells of host defense and a safe turnover of these potentially harmful cells. Alterations of neutrophil apoptosis are associated with a number of diseases.
Taco W. Kuijpers +3 more
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Regulation of the neutrophil life span by apoptosis provides a fine balance between their function as effector cells of host defense and a safe turnover of these potentially harmful cells. Alterations of neutrophil apoptosis are associated with a number of diseases.
Taco W. Kuijpers +3 more
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1989
The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
O. D. Laerum, H. B. Benestad
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The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
O. D. Laerum, H. B. Benestad
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British Medical Bulletin, 1984
Eosinophils are strongly implicated as a major proinflammatory cell in the pathogenesis of asthma. Basic proteins from the crystalloid granule may be responsible for damage to mucosal epithelium whereas membrane-derived lipid mediators (particularly platelet activating factor and leukotriene C4) might directly influence bronchial smooth muscle ...
A. B. Kay, Christopher Corrigan
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Eosinophils are strongly implicated as a major proinflammatory cell in the pathogenesis of asthma. Basic proteins from the crystalloid granule may be responsible for damage to mucosal epithelium whereas membrane-derived lipid mediators (particularly platelet activating factor and leukotriene C4) might directly influence bronchial smooth muscle ...
A. B. Kay, Christopher Corrigan
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Liver tumour immune microenvironment subtypes and neutrophil heterogeneity
Nature, 2022Ruidong Xue +14 more
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Neutrophil extracellular traps and neutrophilic asthma
Respiratory MedicineThere are more than 260 million asthma patients worldwide. How to provide targeted long-term standardized treatment and management still confuses clinical workers and patients. Neutrophilic asthma is a special type of asthma which is difficult to diagnose clinically and often associated with severe asthma and glucocorticoid resistance.
Jiayi Xiang, Muyan Cui, Yuling Zhang
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1984
Neutrophils are short-lived, highly specialized phagocytes. Their main function is to defend the host organism against invading microbes. The properties required to perform this function are chemotactic responsiveness, mobility, and the ability to phagocytose. Microorganisms are sensed through the chemotactic signals they emit or induce; are approached
Beatrice Dewald, Marco Baggiolini
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Neutrophils are short-lived, highly specialized phagocytes. Their main function is to defend the host organism against invading microbes. The properties required to perform this function are chemotactic responsiveness, mobility, and the ability to phagocytose. Microorganisms are sensed through the chemotactic signals they emit or induce; are approached
Beatrice Dewald, Marco Baggiolini
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Elevated neutrophil function in chronic neutrophilic leukemia
American Journal of Hematology, 1992AbstractA 65‐year‐old man with marked leukocytosis was admitted for diagnosis and treatment. His peripheral blood leukocyte count was 37,500/μI and the leukocytes consisted of mature neutrophil‐like cells. A high neutrophil alkaline phosphatase score and a normal bone marrow cell karyotype suggested that the patient had chronic neutrophilic leukemia ...
Yoshifusa Matsuura +7 more
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