Results 111 to 120 of about 165,081 (309)

Neutrophil to lymphocyte ratio and clinical outcomes in COPD: recent evidence and future perspectives [PDF]

, 2018
Chronic obstructive pulmonary disease (COPD) is a disabling condition that is characterised by poorly reversible airflow limitation and inflammation. Acute exacerbations of COPD are a common cause of hospitalisation and death among COPD patients. Several
Carru, Ciriaco, Fois, Alessandro Giuseppe, Mangoni, Arduino A., Negri, Silvia, Paliogiannis, Panagiotis, Pirina, Pietro, Sotgia, Salvatore, Zinellu, Angelo, Zinellu, Elisabetta   +8 more
core   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio, Lymphocyte-to-Monocyte Ratio and Platelet-to-Lymphocyte Ratio as Predictors of Short- and Long-Term Outcomes in Ischemic Stroke Patients with Atrial Fibrillation

Journal of Inflammation Research
Jiahuan Guo,1 Dandan Wang,1 Jiaokun Jia,1 Jia Zhang,1 Yanfang Liu,1 Jingjing Lu,1,2 Xingquan Zhao,1– 4,* Jing Yan1,* 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2China ...
Guo J, Wang D, Jia J, Zhang J, Liu Y, Lu J, Zhao X, Yan J   +7 more
doaj  

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

Advanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas, Sarah E. Miller, Shounak Roy, Jeevika Thazhaiselvam, Samantha Foster, Manivannan Sivaperuman Kalairaj, Sasha M. George, Yava Jones‐Hall, Staci J. Horn, Fred J. Clubb, Taylor H. Ware, Duncan J. Maitland, Akhilesh K. Gaharwar   +12 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Systemic Immune Inflammation Index and Efficacy of Remote Ischemic Conditioning in Acute Ischemic Stroke: A Post Hoc Exploratory Analysis of the RICAMIS Study

Journal of Inflammation Research
Qi Wang,1,2,* Wen-Na Li,3,* Wuxiyar Otkur,4 Yu Cui,1 Hui-Sheng Chen1,2 1Department of Neurology, General Hospital of Northern Theater Command, Shenyang, 110016, People’s Republic of China; 2Dalian Medical University, Dalian, People’s Republic of ...
Wang Q, Li WN, Otkur W, Cui Y, Chen HS
doaj  

NHANES-based assessment of neutrophil-percentage-to-albumin and neutrophil-to-lymphocyte ratios as moderate predictors of mortality in adults with chronic respiratory diseases

Frontiers in Pharmacology
ObjectiveThis study aimed to evaluate the predictive roles of hematologic inflammatory biomarkers, including the neutrophil-percentage-to-albumin ratio (NPAR), neutrophil-to-lymphocyte ratio (NLR), and eosinophil-to-lymphocyte ratio (ELR), in relation to
Feng Xu, Pan Jiang
doaj   +1 more source

Systematic review and meta-analysis of the prognostic significance of Neutrophil-Lymphocyte Ratio (NLR) After R0 gastrectomy for cancer [PDF]

, 2018
Purpose A meta-analysis was performed to evaluate the prognostic value of neutrophil-lymphocyte ratio (NLR) in patients undergoing potentially curative gastrectomy for cancer (GC).
Lewis, Wyn G., Mellor, Katie L., Powell, Arfon G. M. T.   +2 more
core   +2 more sources

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Comparison of Neutrophil-to-Albumin Ratio and Neutrophil-to-Lymphocyte Ratio in Acute Phase Positive and Negative Ankylosing Spondylitis Patients

Haseki Tıp Bülteni
Aim: Acute phase reactants may not always be positive in ankylosing spondylitis (AS). We herein aimed to investigate whether the neutrophil-to-albumin ratio (NAR) is useful in monitoring AS activity.
Beliz Karatas
doaj   +1 more source

Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer [PDF]

, 2017
Background: How systemic inflammation-based prognostic scores such as the modified Glasgow Prognostic Score (mGPS) and neutrophil:lymphocyte ratio (NLR) differ across populations of patients with colorectal cancer (CRC) remains unknown.
Aoki, Taku, Horgan, Paul G., Ishizuka, Mitsuru, Iwasaki, Yoshimi, Kubota, Keiichi, McMillan, Donald C., McSorley, Stephen T., Nagata, Hitoshi, Park, James H., Roxburgh, Campbell S.D., Takagi, Kazutoshi   +10 more
core   +1 more source