Results 51 to 60 of about 165,081 (309)

The preoperative platelet to neutrophil ratio and lymphocyte to monocyte ratio are superior prognostic indicators compared with other inflammatory biomarkers in ovarian cancer

Frontiers in Immunology, 2023
BackgroundPrevious studies have suggested that the ratios of immune-inflammatory cells could serve as prognostic indicators in ovarian cancer. However, which of these is the superior prognostic indicator in ovarian cancer remains unknown.
Qian Song, Song-Xiao Xu, Jun-Zhou Wu, Lin Ling, Sheng Wang, Xin-Hua Shu, Dan-Ni Ying, Wang-Wei Pei, Yu-Chen Wu, Su-Fang Sun, Yi-Ning Zhang, Si-Hang Zhou, Zhu-Yan Shao   +12 more
doaj   +1 more source

Prognostic Value of Computed Tomography : Measured Parameters of Body Composition in Primary Operable Gastrointestinal Cancers [PDF]

, 2017
Professor Graeme Murray, Department of Pathology, University of Aberdeen provided us access to the colorectal cancer pathology databases from which the colorectal component of the research was based.
Black, Douglas, Hamoodi, Zaid, Loudon, Malcolm, MacKay, Craig, Nanthakumaran, Shayanthan, Park, Kenneth G. M., Ramsay, George, Richards, Colin H.   +7 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

The Utility of Peripheral Blood Leucocyte Ratios as Biomarkers in Neonatal Sepsis: A Systematic Review and Meta-Analysis

Frontiers in Pediatrics, 2022
BackgroundEarly stage diagnosis of neonatal sepsis (NS) remains a major roadblock due to non-specific symptoms and the absence of precise laboratory index tests.
Juanjuan Zhang, Jun’an Zeng, Liangjuan Zhang, Xiping Yu, Jinzhen Guo, Zhankui Li   +5 more
doaj   +1 more source

Evaluation of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Chronic Plaque Psoriasis

Indian Journal of Dermatology, 2022
Background: Psoriasis is a common inflammatory dermatological condition and affects 2–3% population worldwide. Psoriasis area and severity index (PASI) and body surface area (BSA) are two commonly used scales used to measure disease severity in psoriasis patients.
Sudeshna Mondal, Samudra Guha, Abanti Saha, Loknath Ghoshal, Debabrata Bandyopadhyay   +4 more
openaire   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Platelet-to-lymphocyte ratio is correlated with a delay in feeding resumption following a transhiatal esophagectomy with cervical anastomosis

World Journal of Surgical Oncology, 2020
Introduction The lymphocytic population, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are prognostic tools predictive of adverse outcomes for several solid tumors and oncologic surgeries, one of which is esophageal ...
Antoine El Asmar, Elie Ghabi, Toufic Saber, Christina Abou-Malhab, Bernard Akl, Ziad El Rassi   +5 more
doaj   +1 more source

Potential mechanism of action of J5 vaccine in protection against severe bovine coliform mastitis. [PDF]

, 2002
Coliform mastitis is one of the most difficult diseases to treat in the modern dairy industry. Curative therapy with antibiotics remains only moderately effective and depends on the stage at which the disease is treated, The most successful strategies ...
Burvenich, Christian, Dosogne, Hilde, Vangroenweghe, Frédéric   +2 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Pretreatment Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Prognostic Factors and Reference Markers of Treatment Options for Locally Advanced Squamous Cell Carcinoma Located in the Middle and Upper Esophagus

Cancer Management and Research, 2021
Chen Wang,1,* Jiaqi Tong,2,* Mengqiu Tang,3 Yunyun Lu,3 Gaofeng Liang,4 Zhanchun Zhang,3 Tian Chen3 1Department of Gastroenterology, Ningbo Medical Center, Lihuili Hospital, Ningbo, People’s Republic of China; 2Department of Hematology, Ningbo ...
Wang C, Tong J, Tang M, Lu Y, Liang G, Zhang Z, Chen T   +6 more
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