Results 261 to 270 of about 1,037,717 (382)

An Unusual Neutrophil Cycle in Down's Syndrome and Acute Leukemia [PDF]

open access: bronze, 1970
Renato Mastrangelo   +3 more
openalex   +1 more source

Topoisomerase I Inhibition in ETV4‐overexpressed Non‐Small Cell Lung Cancer Promotes Replication and Transcription Mediated R‐Loop Accumulation and DNA Damage

open access: yesAdvanced Science, EarlyView.
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang   +14 more
wiley   +1 more source

Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype

open access: yesEuropean Heart Journal, 2016
M. Horckmans   +8 more
semanticscholar   +1 more source

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

open access: yesAdvanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui   +19 more
wiley   +1 more source

CD16 and Siglec expression refine the phenotypic heterogeneity of steady-state myeloid-derived suppressor cells. [PDF]

open access: yesFront Oncol
St Laurent CD   +6 more
europepmc   +1 more source

EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells

open access: yesAdvanced Science, EarlyView.
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li   +15 more
wiley   +1 more source

The trapping of live neutrophils by macrophages during infection. [PDF]

open access: yesCell Death Dis
Cooper KN   +10 more
europepmc   +1 more source

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

open access: yesNature Network Boston, 2015
Siu Ling Wong   +7 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy