Results 81 to 90 of about 106,908 (290)

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy   +8 more
wiley   +1 more source

Señales del cambio global en el sitio LTER-Sierra Nevada

open access: yesEcosistemas, 2016
La investigación ecológica a largo plazo proporciona información útil para comprender las complejas dinámicas de los sistemas naturales. Esto se hace especialmente importante en las regiones de montaña como Sierra Nevada, que presenta un fuerte gradiente
A.J. Pérez-Luque   +5 more
doaj  

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

open access: yesAdvanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou   +9 more
wiley   +1 more source

Characteristics of the demand structure for standing timber and logs in the Central Sierra Nevada region

open access: yesCalifornia Agriculture, 1961
Research on the characteristics of the market for standing timber—stumpage—and logs from small woodlands of less than 5,000 acres, was started in 1957 in the forested portions of El Dorado, Placer, and Nevada counties west of the Sierra Nevada summit.
D Teeguarden
doaj  

Surface motion of active rock glaciers in the Sierra Nevada, California, USA: inventory and a case study using InSAR

open access: yes, 2013
. Despite the abundance of rock glaciers in the Sierra Nevada of California, USA, few efforts have been made to measure their surface flow. Here we use the interferometric synthetic aperture radar (InSAR) technique to compile a benchmark inventory ...
Lin Liu   +3 more
semanticscholar   +1 more source

Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling

open access: yesAdvanced Science, EarlyView.
By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu   +17 more
wiley   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

open access: yesAdvanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang   +23 more
wiley   +1 more source

Extracting ore, mining groundwater: Governmental indicators and the politics of water rights for the mining industry in Nevada, USA

open access: yesWater Alternatives
In this paper we address governmentality and the politics of water rights by examining the Nevada Division of Water Resources (the Division)’s governance associated with water indicators and accounting practices.
Kate A. Berry   +4 more
doaj  

Magnetoelectric Nanoparticle‐Based Wireless Brain–Computer Interface: Underlying Physics and Projected Technology Pathway

open access: yesAdvanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy