Sinonasal mucosal melanoma: Molecular profile and therapeutic implications from a series of 32 cases [PDF]
, 2013 BACKGROUND: Primary sinonasal mucosal melanomas are aggressive tumors with a poor clinical control by current treatments, raising the urgent need of novel strategies.
Balzarini, P. +14 more
core +2 more sources
Rare diseases leading to childhood Glaucoma. epidemiology, pathophysiogenesis, and management [PDF]
, 2015 Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of
Abdolrahimzadeh, Solmaz +5 more
core +3 more sources
The use of 1320nm Nd:YAG laser for the treatment of acne scar in Asians [PDF]
, 1995 published_or_final_versio
Trendell-Smith, NJ +3 more
core +2 more sources
A review of the role of ultrasound biomicroscopy in glaucoma associated with rare diseases of the anterior segment [PDF]
, 2016 Ultrasound biomicroscopy is a non-invasive imaging technique, which allows high-resolution evaluation of the anatomical features of the anterior segment of the eye regardless of optical media transparency.
Abdolrahimzadeh, B +5 more
core +2 more sources
Ocular manifestations of Sturge–Weber syndrome: pathogenesis, diagnosis, and management [PDF]
, 2016 Sturge-Weber syndrome has been included in the group of phakomatoses that is characterized by hamartomas involving the brain, skin, and eyes. The characteristic facial port-wine stain, involving the first branch of the trigeminal nerve and the embryonic ...
Abdolrahimzadeh, Solmaz +4 more
core +1 more source
An Unusual Melanocytic Nevus of Conjunctiva : Balloon Cell Nevus [PDF]
, 2011 Melanocytic nevi are one of the most common benign tumors of the conjunctiva. The balloon cell nevus is a rare and unusual variant of nevus of melanocytic origin, in which more than 50% of the tumor is composed of large polygonal cells with small nucleus
Geethalakshmi, U +3 more
core
G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers
MedComm, Volume 6, Issue 10, October 2025.G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan +6 more
wiley +1 more source
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. [PDF]
, 2009 BRAF and NRAS are common targets for somatic mutations in benign and malignant neoplasms that arise from melanocytes situated in epithelial structures, and lead to constitutive activation of the mitogen-activated protein (MAP) kinase pathway.
Barsh, Gregory S +8 more
core
Q-switched Nd:YAG laser to manage hyperpigmentation in asians. a multicenter study [PDF]
, 2023 (1) Introduction: In cosmetic dermatology, benign hyperpigmentation is a prevalent issue. Solar lentigo and other melanoses are bringing patients to the attention of physicians more and more often. The Q-switched 1064/532-nanometer (nm) laser is the gold
Amoruso G. F. +6 more
core +1 more source
A Case of Iris Mammillation Associated with Nevus of Ota [PDF]
, 2013 Nevus of Ota is characterized by the presence of hyperpigmentation in the skin areas innervated by the first or the second branches of the trigeminal nerve. Women are affected three times as often as men.
Kacar, Seval Dogruk +2 more
core +1 more source