Exploring the interdependencies of research funders in the UK [PDF]
, 2014 Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P +13 more
core +1 more source
Varied presentation of congenital dermal melanocytosis with speckled lentigines
Indian Journal of Dermatopathology and Diagnostic DermatologyNevus of Ota and nevus of Ito are rare dermal melanocytosis. These occur due to the failure of migration of melanocytes from the neural crest to the epidermis. They are more common in Asian females and usually present at birth.
Seema Rani +2 more
doaj +1 more source
G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers
MedComm, Volume 6, Issue 10, October 2025.G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan +6 more
wiley +1 more source
Preneoplasias cutáneas y de mucosa oral [PDF]
, 2018 Este trabajo hace foco sobre aquellas dermatosis que pueden dar origen a tumores. Enfatiza el reconocimiento de las mismas a partir del examen clínico y de los métodos de laboratorio que aseveran ese diagnóstico.
Driban, Nelson E. +2 more
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A Case of Iris Mammillation Associated with Nevus of Ota [PDF]
, 2013 Nevus of Ota is characterized by the presence of hyperpigmentation in the skin areas innervated by the first or the second branches of the trigeminal nerve. Women are affected three times as often as men.
Kacar, Seval Dogruk +2 more
core +1 more source
Cervical Intradural Extramedullary Melanocytoma , Associated with Nevus of Ito. Recurrence and Long-Term Outcome [PDF]
, 2023 Background: Melanocytoma is a rare pigmented central nervous tumor. In the spine, it may develop in meninges, extramedullary or intramedullary. It usually has good outcome after total excision.
Abuajamieh, Zaid +10 more
core +2 more sources
Estudio epidemiológico transversal observacional de nevus melanocítico en adolescentes. Propuesta de manejo desde Atención Primaria [PDF]
, 2019 Este trabajo se centra en el estudio de los nevus melanocíticos y sus diferentes características y persigue los siguientes objetivos: perfil epidemiológico y características de los pacientes adolescentes derivados con lesiones melanocíticas; concordancia
Alba Martínez, Cristina de
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Report of rare palatal expression of Nevus of Ota with amendment of Tanino′s classification
Indian Journal of Dental Research, 2011 Nevus of Ota, a benign melanocytic pigmentary disorder with rare malignant transformation potential, affects 0.014-0.034% of the Asian and Black population and has a strong predilection for females.
Mahima V Guledgud +3 more
doaj +1 more source
Role of enhancer of zeste homolog 2 polycomb protein and its significance in tumor progression and cell differentiation [PDF]
, 2013 Epigenetics is a branch of genetics that focuses on the heritable changes of DNA or associated proteins, other than DNA sequence variations, which carry information content during cell division [1,2].
Bagella, Luigi Marco, Marchesi, Irene
core +2 more sources
Dermoscopy Assisting Diagnosis of Dermal Melanocytosis Limited to the Hand
Clinical Case Reports, Volume 13, Issue 6, June 2025.ABSTRACT Acquired dermal melanocytosis (ADM) is a skin disorder characterized by the presence of melanocytes in the dermis. The face is the most common site of ADM. ADM can be difficult to diagnose when it occurs in an unusual clinical setting.
Manni Huang +4 more
wiley +1 more source