Results 91 to 100 of about 3,985,796 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
RUDN journal of SociologyThe article considers history, prerequisites and consequences of the spread of New Age ideas and practices in contemporary society as a new form of spirituality that contributes to the emergence and spread of new religious movements (NRMs).
T. A. Khagurov, M. G. Rudakov
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Spiritüel Ağ: Sosyal Medya ve Yön Değiştiren İnanışlar Üzerine Bir İnceleme
Medya ve KültürBu çalışma, Gülenay Pınarbaşı’nın 2021 yılında kitaplaştırdığı “Spiritüel Ağ: Sosyal Medya ve Yön Değiştiren İnanışlar” adlı çalışması hakkında bir kitap incelemesidir.
Meryem İlayda Atlas
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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New Dark Age Ensemble, October 27, 1997, Ulrich Recital Hall, University of Maryland
, 1997 Audio recording of a live performance by the New Dark Age Ensemble. The performance occurred on October 27, 1997 in the Ulrich Recital Hall at the University of Maryland.
New Dark Age Ensemble
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
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Caderno CRHO presente trabalho tem como objeto de estudo a experiência dos ecocaminhantes, um grupo de praticantes de caminhadas ecológicas que, apostando no cultivo de um bem-estar físico, mental e espiritual, realiza caminhadas em meio à natureza.
Carlos Alberto Steil, Rodrigo Toniol
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