Results 191 to 200 of about 29,602,681 (295)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

An Application of the Matrix Method in Physiological Psychology Research Planning

Operations Research ...
Mathis, Samuel J., Jr. (Creatorcre), Salkin, Harvey (Creatorcre), Chandrasekaran, R. (Creatorcre), Dean, Burton V. (Creatorcre)   +3 more
core  

A Twisting Diagnosis: A New Case of VPS16-Related Hyperkinetic Spectrum and Literature Review. [PDF]

Mov Disord Clin Pract
Fontanesi D, Saccardin G, Monfrini E, Panteghini C, Argenziano G, Bisquoli M, Coniglio S, Di Fonzo A, Garavaglia B, Rispoli V.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Applications of Integer Programming to Radio Frequency Management

Operations Research ...
Nishimura, Koichi (Creatorcre)
core  

PAK1 (p21-Activated Kinase 1) and Its Role in Neurodevelopmental Disorders-New Case Report and a Comprehensive Review. [PDF]

Int J Mol Sci
Blek N, Pielas M, Kharytonov V, Rutkowska K, Rusecka J, Lewicki S, Płoski R, Zwoliński P.   +7 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Analysis of Runway Operations

Operations Research ...
Schrady, David A. (Creatorcre)
core  

Nosocomial oral myiasis caused by <i>Chrysomya bezziana</i> in Iran: A new case and review of human myiasis in the country. [PDF]

IDCases
Mirbadie SR, Mohaghegh MA, Skandary F, Soleymani E, Nikbin F, Sazmand A.   +5 more
europepmc   +1 more source

Control of dermatomyositis skin disease activity lags behind control of muscles disease activity during the early treatment stages of classic dermatomyositis: A retrospective, single‐centre study

Skin Health and Disease
Heeruk Bhatt, Elizabeth M. Flatley, Kevin D. Cooper, Trine N. Jorgensen, Christine McDonald, Anthony P. Fernandez   +5 more
doaj   +1 more source