Results 201 to 210 of about 18,270,200 (290)

Facilitating the timely diagnosis of Lennox–Gastaut syndrome: A checklist to support clinical practice

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective To develop and evaluate a simple‐to‐use checklist to support physicians with the timely diagnosis of Lennox–Gastaut syndrome (LGS). Methods A panel of 10 pediatric and adult epileptologists used the International League Against Epilepsy (ILAE) criteria for LGS classification and definition to develop seven questions for the checklist,
Nicola Specchio   +9 more
wiley   +1 more source

Video‐based diagnostics supported by artificial intelligence as an opportunity to address the epilepsy diagnostic gap: A narrative review

open access: yesEpilepsia, EarlyView.
Abstract Despite advancements in epilepsy care, a substantial diagnostic gap persists, particularly in resource‐limited settings. This narrative review explores the potential of video‐based diagnostics augmented by artificial intelligence (AI) to address this gap by enabling earlier and more accessible seizure detection and classification.
Gadi Miron   +7 more
wiley   +1 more source

Clinical significance of subclinical seizures in epilepsy presurgical evaluation: A systematic review and meta‐analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug‐resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes.
Pilar Bosque‐Varela   +6 more
wiley   +1 more source

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n 
Sophie von Brauchitsch   +27 more
wiley   +1 more source

Mutant and Wild-Type RAS Cross-talk and Stoichiometric Deficiencies Are Determinants of Sensitivity to Targeted Therapies in KRASG12R Pancreatic Ductal Adenocarcinoma. [PDF]

open access: yesCancer Res
Kamgar M   +26 more
europepmc   +1 more source

Status epilepticus in adults: From etiology to treatment response

open access: yesEpilepsia, EarlyView.
Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi   +5 more
wiley   +1 more source

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