Results 171 to 180 of about 18,893,691 (203)

Clinical significance of subclinical seizures in epilepsy presurgical evaluation: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract Objective Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug‐resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes.
Pilar Bosque‐Varela, Panagiota‐Eleni Tsalouchidou, Petra Levicka, Lara Wadi, Elizabeth R. Blackwood, Eugen Trinka, Birgit Frauscher   +6 more
wiley   +1 more source

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n 
Sophie von Brauchitsch, Nils Hartung, Robin A. Karge, Bobby Koeleman, Samuel F. Berkovic, Danielle M. Andrade, Francesca Bisulli, Antonio Gambardella, Renzo Guerrini, Ingrid E. Scheffer, Ingo Helbig, Wolfram S. Kunz, Holger Lerche, Hiltrud Muhle, Christian Boßelmann, Savvas S. Papacostas, Mark I. Rees, Sanjay M. Sisodiya, Pasquale Striano, Lynnette Sadleir, Yvonne Weber, Dennis Lal, Costin Leu, Philipp S. Reif, Stefan Wolking, Felix Rosenow, Karl Martin Klein, for the Epi25 Collaborative   +27 more
wiley   +1 more source

Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus

Epilepsia, EarlyView.
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger, Pilar Bosque‐Varela, Jürgen Steinbacher, Johannes Pfaff, Eugen Trinka, Giorgi Kuchukhidze   +5 more
wiley   +1 more source

Deep whole genome sequencing of epileptogenic brain lesions

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development and low‐grade epilepsy‐associated tumors often cause drug‐resistant lesional focal epilepsy (LFE) amenable to surgical treatment. Genetic testing of resected brain tissue can provide diagnostic and mechanistic information and may eventually support personalized treatment approaches.
Christian M. Boßelmann, Costin Leu, Lucas Hoffmann, Roland Coras, Katja Kobow, Hajo Hamer, Daniel Delev, Christian G. Bien, Thilo Kalbhenn, Tom Pieper, Till Hartlieb, Kerstin Becker, Lisa Ferguson, Robyn M. Busch, Peter Nürnberg, Imad Najm, Ingmar Blümcke, Dennis Lal   +17 more
wiley   +1 more source

Artificial intelligence‐assisted categorization of interictal abnormalities in adult long‐term electroencephalographic monitoring: Comparable diagnostic accuracy with marked efficiency gain

Epilepsia, EarlyView.
Abstract Objective Artificial intelligence (AI) classifies routine electroencephalograms (EEGs) with expert‐level accuracy, but interpretation of long‐term EEG monitoring (LTM) remains reliant on time‐intensive visual review. We evaluated whether autoSCORE, a clinically approved implementation of SCORE‐AI integrated into an EEG reader, achieves expert ...
Daniel Mansilla, Jesper Tveit, Harald Aurlien, Tamir Avigdor, Chifaou Abdallah, Pilar Bosque‐Varela, Melita Cacic Hribljan, Victoria Ros‐Castelló, Donald Schomer, Jean Gotman, Sandor Beniczky, Birgit Frauscher   +11 more
wiley   +1 more source

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

Epilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi, Jonathan Ipser, James T. Butler, Heath Pardoe, Hamid Soltanian‐Zadeh, Christian Rummel, Roland Wiest, Simon S. Keller, Barbara A. K. Kreilkamp, Anna Elisabetta Vaudano, Alice Ballerini, Stefano Meletti, Gerard Hall, Peter Taylor, Luis Concha, Alfonso Fajardo‐Valdez, Raphael Fernandes Casseb, Fernando Cendes, Clarissa L. Yasuda, Louis Lemieux, John S. Duncan, Esmaeil Davoodi‐Bodj, Orrin Devinsky, Sophia I. Thomopoulos, Dan J. Stein, Paul M. Thompson, Sanjay M. Sisodiya, Taha Gholipour, Carrie R. McDonald   +28 more
wiley   +1 more source

A'mmomat and weshu processing as a mechanism of balancing gender power relations among the Kambaata community of Central Ethiopia

Feminist Anthropology, EarlyView.
Abstract This article argues that power in gender relations within the Kambaata people of central Ethiopia is expressed through relational, mutual, and complementary dynamics rather than domination or control. It critiques Western liberal feminist frameworks—especially those emphasizing rights, equality, and resistance—for their limitations in ...
Desta Lorenso
wiley   +1 more source

Embodied attachments: IVF, the maternal body, and the making of embryo kinship

Feminist Anthropology, EarlyView.
Abstract Within the sphere of IVF (in vitro fertilization), there is increasing concern about the stockpiles of frozen embryos held in clinics across the country. This normative discourse tends to take the patient‐embryo relationship for granted, with salient political consequences for current embryo ‘personhood’ debates.
Manon Lefevre
wiley   +1 more source

Medical Brain Drain: The Role of Job Attributes and Individual Traits

Health Economics, EarlyView.
ABSTRACT Medical brain drain poses a major challenge for health systems, reducing physician supply and undermining public investment in medical training. Prior work examined migration flows and their macroeconomic determinants. This study uses a discrete choice experiment to assess how individual background and personality traits shape medical student ...
Marco Bertoni, Debdeep Chattopadhyay, Yuanyuan Gu   +2 more
wiley   +1 more source

Barriers and Facilitators to the Implementation of the Weekend‐70 Cervical Cancer Screening Programme in Mali: A Multiple Case Study

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction Cervical cancer (CC) represents a significant public health issue in low‐ and middle‐income countries. In Mali, the Weekend‐70 cervical cancer screening programme, initially implemented in Bamako (the capital), is gradually being rolled out in other regions.
Aminata Adama Ndour, Sabina Abou Malham, David‐Martin Milot, Geneviève Baron, Ibrahima Téguété, Mahamane Maiga, Kadidia Bokar   +6 more
wiley   +1 more source