Results 81 to 90 of about 8,159,296 (302)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A new combination and change in rank in Polycarpon (Caryophyllaceae), endemic to California, U.S.A., and Mexico [PDF]
, 2015 The name Polycarpon depressum Nutt. (Caryophyllaceae) is here investigated and lectotypified. According to a recent molecular investigation and based on the morphology and ecology of the taxon, the new combination and change in rank for P.
IAMONICO, DUILIO
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Top Quark Pair Production Cross Section and Forward-Backward Asymmetry at the Tevatron [PDF]
, 2008 We present recent results on top quark pair production cross section and forward-backward asymmetry at the Tevatron. Three new cross section measurements from CDF and one new measurement from DO are presented that utilize the full dataset available.
Lister, Alison
core +1 more source
Highly active iridium(I) complexes for the selective hydrogenation of carbon-carbon multiple bonds [PDF]
, 2011 New iridium(I) complexes, bearing a bulky NHC/phosphine ligand combination, have been established as extremely efficient hydrogenation catalysts that can be used at low catalyst loadings, and are compatible with functional groups which are often ...
Andersson, Shalini +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Una nueva combinación en Steriphoma paradoxum (Jacq.) Endl. (Capparaceae)
Anales del Jardín Botánico de Madrid, 2006 Steriphoma paradoxum (Jacq.) Endl. subsp. venezolanum (Briq.) X. Cornejo is proposed as a new combination because of marked differences in gynophores, stamens, and pedicels between the Mesoamerican and Venezuelan populations.
Xavier Cornejo
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source