Results 121 to 130 of about 85,437 (270)
Annals of Neurology, EarlyView.Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
Relapsing-remitting multiple sclerosis: advances in disease-modifying therapies [PDF]
, 2015 Multiple sclerosis is a demyelinating disease affecting the central nervous system. It is the most prevalent disabling neurological condition among young adults, with onset typically between 20 and 40 years of age. Infiltrating immune cells and microglia
Kay, Kathleen Alexandra
core +1 more source
Auditory Stimulation of Slow‐Wave Sleep Promotes Recovery after Brain Injury in an Animal Model
Annals of Neurology, EarlyView.Objective Traumatic brain injury (TBI) significantly reduces the quality of life for millions of survivors worldwide, causing persistent brain tissue damage and cognitive impairments, with no established therapeutic interventions currently available.
Carlos G. Moreira +9 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2013 Neuropathic pain (NP) of head or face commonly consists of trigeminal neuralgia, glossopharyngeal neuralgia, occipital neuralgia, and postherpetic neuralgia, which is often reported as having lancinating, burning or lightning pain and is often associated
Zhao DONG, Sheng-yuan YU
doaj
Arthritis &Rheumatology, EarlyView.Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller +15 more
wiley +1 more source
Journal of the Association for Information Science and Technology, EarlyView.Abstract The emergence of generative artificial intelligence (GenAI) is reshaping the research landscape and carries significant implications for Digital Humanities (DH), a field long intertwined with computational methods and technologies. This study examines how DH scholars are adopting and critically evaluating GenAI in their research. Drawing on an
Rongqian Ma, Meredith Dedema, Andrew Cox
wiley +1 more source
New Daily Persistent Headache-A Start With an Uncertain End. [PDF]
JAMA Neurol, 2022 Gelfand AA, Robbins MS, Szperka CL.
europepmc +1 more source
Psychological Impact of Autism Screening on Caregivers
Autism Research, EarlyView.ABSTRACT Autism screening in childhood is common, yet little is known about its potential psychological impact on caregivers. The U.S. Preventive Services Task Force, an independent national panel of disease prevention experts, stated that this gap in knowledge limited their ability to endorse universal autism screening.
Ramkumar Aishworiya +6 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Uses of Botulinum Toxin in Headache and Facial Pain Disorders: An Update
ToxinsBotulinum toxin is a neurotoxin that is used in the treatments for several medical conditions, such as dystonia, spasticity, hemifacial spasm, overactive bladder, and hyperhidrosis.
Pedro Augusto Sampaio Rocha-Filho +3 more
doaj +1 more source