PregnancyIntroduction Virtual maternity solutions vary widely in clinical depth, and their association with physiological outcomes in high‐risk populations remains understudied.
Lena Bertozzi +5 more
doaj +1 more source
To Compress or Not to Compress—Self-Supervised Learning and Information Theory: A Review
EntropyDeep neural networks excel in supervised learning tasks but are constrained by the need for extensive labeled data. Self-supervised learning emerges as a promising alternative, allowing models to learn without explicit labels.
Ravid Shwartz Ziv, Yann LeCun
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Variation in activation marker expression within the platelet population – a new parameter for evaluation of platelet flow cytometry data [PDF]
, 2022 Nahreen Tynngård +3 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Capital Structure Determinants: New Evidence from French Panel Data
, 2011 Mondher Kouki, Hatem Ben Said
openalex +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Vertical Transmission of Dengue Virus in the Peripartum Period and Viral Kinetics in Newborns and Breast Milk: New Data [PDF]
, 2016 Lucille Arragain +9 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Development of the Rheumatic Fever Care Coordination System (RFCCS) for Aotearoa New Zealand
ProceedingsRates of acute rheumatic fever (ARF) and rheumatic heart disease (RHD) among New Zealand Māori and Pacific are among the highest reported in high-income countries [...]
Catherine Jackson +8 more
doaj +1 more source