Results 191 to 200 of about 20,278,496 (338)

New data on the huntsman spiders (Araneae, Sparassidae) of China. [PDF]

Biodivers Data J
Hu C, Zhang H, Zhong Y.
europepmc   +1 more source

On the Benchmarking of New Evaluated Nuclear Data Libraries [PDF]

, 2018
Andrej Trkov
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Hepatitis E Virus Infection in a Hospital from Southern Romania-New Data About a Threat to Public Health. [PDF]

Microorganisms
Popescu C, Cireșă A, Popescu GA, Vasile CC, Bănică LM, Florea D.   +5 more
europepmc   +1 more source

Comparative analysis of human mobility patterns: utilizing taxi and mobile (SafeGraph) data to investigate neighbourhood-scale mobility in New York City

Yuqin Jiang, Su Yeon Han, Zhenlong Li, Huan Ning, Joon‐Seok Kim   +4 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Hemitaeniochromis pumba, a new species of cichlid fish from Lake Malawi, Africa, with comments on related species (morphometric and meristic data)

Turner, George Francis
openalex   +1 more source

RWD188 Unlocking the Potential of Interoperable Linked Low-Latency National Health Data in England to Protect Vulnerable Patients While Safeguarding Their Privacy: A Brave New World [PDF]

Nahila Justo, Satomi Izumi Taylor, A. Antonarou, Yi Lu, Sabada Dube, Muhammad Ejaz, Kasey Evans, Carla Talarico, Victoria A. Olson, J. Kasan, D. Turner   +10 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A new data-driven paradigm for the study of avian migratory navigation. [PDF]

Mov Ecol
Demšar U, Zein B, Long JA.
europepmc   +1 more source