Results 221 to 230 of about 20,278,496 (338)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

ASO Author Reflections: Old Truths, New Data: Intraductal Oncocytic Papillary Neoplasm-Derived Pancreatic Cancer Requires Continued Surveillance. [PDF]

Ann Surg Oncol
Hidalgo Salinas C, Habib JR, Javed AA, Sacks GD.   +3 more
europepmc   +1 more source

THE KONDAROS-KATSIMOUTI INTERMEDIATESULFIDATION EPITHERMAL PB-ZN-AG-MN MINERALIZATION, WESTERN MILOS, GREECE: NEW MINERALOGICAL AND GEOCHEMICAL DATA

, 2017
K. Papavasiliou, Panagiotis Voudouris, Christos Kanellopoulos, Dimitrios Alfieris, Stamatios Xydous   +4 more
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

More than half a century of evolutionary studies in Rhodnius prolixus Stål, 1859 (Hemiptera, Triatominae): revisiting and discussing old and new data on intra- and interspecific reproductive barriers. [PDF]

PLoS One
Alevi KCC, Ravazi A, de Oliveira J, Dos Reis YV, Bittinelli IF, Delgado LMG, Santana JKS, de Azeredo-Oliveira MTV, da Rosa JA, Marrelli MT, Galvão C.   +10 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Correction: Sonongbua et al. Insights into Mitochondrial Rearrangements and Selection in Accipitrid Mitogenomes, with New Data on Haliastur indus and Accipiter badius poliopsis. Genes 2024, 15, 1439. [PDF]

Genes (Basel)
Sonongbua J, Thong T, Panthum T, Budi T, Singchat W, Kraichak E, Chaiyes A, Muangmai N, Duengkae P, Sitdhibutr R, Kasorndorkbua C, Srikulnath K.   +11 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

New data on the fauna of the water treaders (Hemiptera, Mesoveliidae) of Korea. [PDF]

Biodivers Data J
Yang S, Kim W.
europepmc   +1 more source

Sticking Innovation and Features: A New Exploration of the Transformation of University Journals Editor in the Age of Big Data

, 2019
Jing Cao
openalex   +1 more source