Results 231 to 240 of about 20,278,496 (338)

Optimization and New Technologies Implementation: Java Application for Data Transmission [PDF]

, 2013
Konograi, N.A., Morozkin, Konstantin, Poperechna, N.V.   +2 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Subfossil Insects of the Kebezen Site (Altai Mountains): New Data on the Last Deglaciation Environment. [PDF]

Insects
Gurina AA, Agrikolyanskaya NI, Dudko RY, Mikhailov YE, Prokin AA, Reshetnikov SV, Sazhnev AS, Solodovnikov AY, Zinovyev EV, Legalov AA.   +9 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Valve replacement during pregnancy: literature review including new data from the Registry Of Pregnancy And Cardiac disease III. [PDF]

Eur J Cardiothorac Surg
van der Zande JA, Siromakha S, Peters PNJ, Youssef G, Galian-Gay L, Ladouceur M, Wells G, Takkenberg JJM, Veen KM, Ramlakhan KP, Hall R, Johnson MR, Roos-Hesselink JW, ROPAC Investigators .   +13 more
europepmc   +1 more source

WaxAlly: NEW SOFTWARE TO IDENTIFY ACYCLIC LIPIDS FROM GAS CHROMATOGRAPHY COUPLED TO MASS SPECTROMETRY DATA

Lucas Paradizo Roma, Déborah Yara Alves Cursino dos Santos   +1 more
openalex   +1 more source

A New Energy Efficient Routing Scheme for Data Gathering

, 2015
S.Mathu Muhila, N. Priyadharshini, G. Sudha, P. Venkateswari, H. Vishali, Christo Ananth   +5 more
openalex   +1 more source

New Data Show Child Sexual Abuse Down 5 Percent Nationally [PDF]

, 2007
Wright, Lori
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Leveraging a new data resource to define the response of Cryptococcus neoformans to environmental signals. [PDF]

Genetics
Kang YS, Jung J, Brown HL, Mateusiak C, Doering TL, Brent MR.   +5 more
europepmc   +1 more source