Results 271 to 280 of about 20,278,496 (338)

Risk Factors for Infusions, Emergency Room Visits and Hospitalizations for Hyperemesis Gravidarum: New Data and Literature Review. [PDF]

Int J Womens Health
de Vera SA, Brecht-Doscher A, Fejzo MS, Brecht ML, Kwon IM, MacGibbon KW.   +5 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Immunotherapy in the treatment landscape of hormone receptor-positive (HR+) early breast cancer: is new data clinical practice changing? [PDF]

ESMO Open
Zagami P, Cortés J, Carey LA, Curigliano G.   +3 more
europepmc   +1 more source

A New Measure of Psychiatric Severity Using Administrative Data: the Manifestations of Psychiatric Severity Index (MoPSI)

Maureen Murdoch, Barbara Clothier, Siamak Noorbaloochi   +2 more
openalex   +1 more source

The technology of polychrome glazed ceramics in Ifriqiya: new data from the site of Chimtou. [PDF]

Archaeol Anthropol Sci
Occari V, Möller H, Fenwick C, Quinn P, Freestone IC, Chaouali M, von Rummel P.   +6 more
europepmc   +1 more source

KoNA: Korean Nucleotide Archive as A New Data Repository for Nucleotide Sequence Data. [PDF]

Genomics Proteomics Bioinformatics
Ko G, Lee JH, Sim YM, Song W, Yoon BH, Byeon I, Lee BH, Kim SO, Choi J, Jang I, Kim H, Yang JO, Jang K, Kim S, Kim JH, Jeon J, Jung J, Hwang S, Park JH, Kim PG, Kim SY, Lee B.   +21 more
europepmc   +1 more source

Contamination of Consensus Sequences in Next-Generation Mitogenomics: The Published Mitochondrial Genome of Haliastur indus Is a Chimera with DNA from Butastur indicus. Comment on Sonongbua et al. Insights into Mitochondrial Rearrangements and Selection in Accipitrid Mitogenomes, with New Data on Haliastur indus and Accipiter badius poliopsis. Genes 2024, 15, 1439. [PDF]

Genes (Basel)
Sangster G, Luksenburg JA.
europepmc   +1 more source