Results 301 to 310 of about 17,089 (357)

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

"Integration is a Gift from God": Blackness, Externalization, and the Figure of the Refugee. [PDF]

Migr Soc
Berhane FS.
europepmc   +1 more source

Liberalization and Democratization in the Context of a Weak State and a Weaker Civil Society [PDF]

Pereira, Luiz Carlos Bresser
core  

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Fixing the earth: whole-systems thinking in Silicon Valley's environmental ideology. [PDF]

Internet Hist
Riemens R.
europepmc   +1 more source

[Book Review of] \u3cem\u3eIn Good Conscience: Abortion and Moral Necessity\u3c/em\u3e, by David Mall [PDF]

, 1983
Crossin, John W.
core   +1 more source

From Nationalism to Post-Developmentalism: The Intersection of Gender, Race and Religion in Malaysia [PDF]

, 2002
Mohamad, Mahnaz Binti
core   +1 more source

Multimodal imaging including OCT-A and functional testing of North Carolina Macular Dystrophy (NCMD) provides new insights into the developmental nature of NCMD and the development of the human macula

, 2018
Kent W. Small, Fadi Shaya, Nitin Udar, Leslie Small, Edwin M. Stone   +4 more
openalex   +1 more source