Results 41 to 50 of about 88,511,412 (257)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
GridPenguin: A District Heating Network Simulator [PDF]
, 2022 District heating system (DHS) optimization is becoming an increasingly important problem because of the unused potential in flexibility that could allow less energy being wasted and the integration of renewable energy.
de Weerdt, M.M. (author) +3 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Nano ResearchHigh-entropy single-atom (HE SAs), distinguished by maximized atomic utilization efficiency and tunable coordination geometries, represent a frontier in atomic-scale electromagnetic wave (EMW) absorber design.
Tong Liu +11 more
doaj +1 more source
Study on Tough Blends of Polylactide and Acrylic Impact Modifier
BioResources, 2014 Acrylic impact modifiers (ACRs) with different soft/hard monomer ratios (mass ratios) were prepared by semi-continuous seed emulsion copolymerization using the soft monomer butyl acrylate and the hard monomer methyl methacrylate, which were used to ...
Xiaoli Song +3 more
doaj +1 more source
CO2 High-Temperature Electrolysis Technology Toward Carbon Neutralization in the Chemical Industry
Engineering, 2023 The chemical industry is a major carbon emitter in China and must be focused on for China to achieve its goal of carbon neutralization. Carbon dioxide (CO2) high-temperature electrolysis based on solid oxide electrolysis cells (SOECs) is an important ...
Yifeng Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Effects of Bio-based Plasticizers on Mechanical and Thermal Properties of PVC/Wood Flour Composites
BioResources, 2014 Poly(vinyl chloride)/wood flour (WPVC) composites with dioctyl phthalate (DOP), dibutyl phthalate (DBP), cardanol acetate (CA), or epoxy fatty acid methyl ester (EFAME) were prepared using twin-screw extrusion.
Zhenhua Xie +5 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
, 2023 Energy poverty measures are gradually becoming less relevant for fast-developing countries, where the energy mix consists of traditional and modern energies. We propose a new approach for measuring energy poverty by modifying the Exact Affine Stone Index
Nguyen, Luan Thanh +2 more
core +1 more source