Results 161 to 170 of about 24,427,038 (311)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

The use of Structural Funds and European Investments (ESI) in order to develop the Member States. Examples of good practice in the use of ESI funds

open access: yesAgora International Journal of Economical Sciences, 2017
Multiannual financial framework of the European Union (EU) for the period 2014-2020 enables implementation of the new generation of EU spending programs since 1 January 2014.
Gabriela Bologa, Casian Butaci
doaj  

What world of work in new EU member states? [PDF]

open access: yes
"The years of transition in Central and Eastern Europe brought with them the unprecedented - in these societies - phenomenon of restructuring with dismissals and growing unemployment. Moreover with the emergence and development of the private sector, new
Vaughan-Whitehead, Daniel
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The EU Midwifery Directive and Professional Strengthening in New EU Member States and Candidate Countries. [PDF]

open access: yesHealthcare (Basel)
Brigante L   +15 more
europepmc   +1 more source

The Potential of ICT for the Development and Economic Restructuring of the New EU Member States and Candidate Countries [PDF]

open access: yes
ICT could help the New Member States catch up with EU-15 in economic terms. The report documents the potential of ICT for improved productivity performance in the Central and Eastern Europe countries (CEE) at the macro and industry level, in relation to ...
Piatkowski, Marcin
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

How flexicure are new EU member states?

open access: yes, 2012
The paper analyses the state of implementation of flexicurity policy components in the NMS and, by using panel regression analysis, estimates the relationship between flexicurity policy components (i.e., employment protection legislation, expenditures for active employment policies, participation in lifelong learning and net replacement rate) and ...
Laporšek, Suzana, Dolenc, Primož
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

EU accession and income growth: an empirical approach [PDF]

open access: yes
The dynamic effects from EU membership are crucial for the new member states to catch up with the average income level in the old member states. To gauge the dynamic effects, we follow a two-step procedure in which a gravity equation for bilateral trade ...
Vlado Solanic, Arjan Lejour, Paul Tang
core  

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