Results 71 to 80 of about 24,427,038 (311)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Management of the Structural Funds within the Context of the Global Economic Crisis [PDF]
The member states which accessed the European Union in 2004 and 2007 progressed through similar financing cycles during the pre-accession period by applying the EU specific principles of positive conditionality.
Corina CACE +2 more
doaj
Implications of EU Enlargement for Agricultural Markets in the New Member States [PDF]
The paper presents an analysis of the impact of the Common Agricultural Policy implementation on the agricultural markets of the eight new EU Member States.
Bartova, Lubica +3 more
core
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Strategic Priorities or Stock Exchanges in New EU Member States [PDF]
This study discusses the strategic priorities and challenges for securities exchanges in new EU member states, with a special reference to the internationalisation of securities markets. The ways in which exchanges are responding to such challenges and other possible courses of action are identified.
openaire +2 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Foreign policies of EU member states: continuity and europeanisation
Foreign Policies of EU Member States provides a clear and current overview of the motivations and outcomes of EU Member States regarding their foreign policy-making within and beyond the EU.
core +1 more source
EU Funds Provided to the New Member States: Relevance for ODA and Achieving the Monterrey Consensus [PDF]
The EU transfers provided to the New Member States and candidate countries are generally viewed as having been efficiently used in promoting development in these economies.
Jaroslaw Pietras
core

