Results 101 to 110 of about 21,961,066 (284)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Military personnel / New Jersey Division of Taxation.

open access: yes, 1999
Tax topic bulletin ; GIT-7 "State of New Jersey, Department of the Treasury, Division of Taxation, Technical Services, Taxpayer Services Branch." Caption ...
New Jersey Division of Taxation
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A new function for drug combination dose finding trials

open access: yesScientific Reports
Combination drugs play an essential role in treating cancers. The challenging part of the combination drugs are to specify the dose-toxicity ordering, which means the sequences of dose escalation and de-escalation in process of dose findings should be ...
Jiacheng Xiao, Weijia Zhang
doaj   +1 more source

New Families of Third-Order Iterative Methods for Finding Multiple Roots

open access: yesJournal of Applied Mathematics, 2014
Two families of third-order iterative methods for finding multiple roots of nonlinear equations are developed in this paper. Mild conditions are given to assure the cubic convergence of two iteration schemes (I) and (II).
R. F. Lin   +5 more
doaj   +1 more source

The New Yorker : the New York University weekly.

open access: yes, 1907
Issues for Nov. 14, 1907-June 7, 1910 published in magazine format; Oct. 17, 1910-May 17, 1910 in newspaper format.Title from cover."A weekly journal devoted to the interests of the students and alumni of New York University."Suspended publication fall ...
New York University.
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Finding

open access: yes, 2018
"Traces the fortunes of two New Zealand families over seven generations, through wars, depressions, disasters, protest and social change"--Publisher informationPrimary ...
Hill, David 1942-
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Federation Hospitals of New York City, Part II

open access: yes, 1941
Digital ImageDigital finding ...
Federation of Jewish Philanthropies of New York
core  

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