Finding a heaviest vertex-weighted triangle is not harder than matrix multiplication [PDF]
We show that a maximum-weight triangle in an undirected graph with n vertices and real weights assigned to vertices can be found in time O(n(omega) + n(2+o(1))), where omega is the exponent of the fastest matrix multiplication algorithm. By the currently
Lingas, Andrzej, +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Inverted U-shaped association between bacillary dysentery and temperature: A new finding using a novel two-stage strategy in multi-region studies. [PDF]
Wang W, Wang Y, Chen L, Zhou B, Liao F.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
New finding of Toxorhina (Ceratocheilus) limoniid fly in Eocene Baltic amber and the biogeographical context of the genus. [PDF]
Kania-Kłosok I +2 more
europepmc +1 more source
One Chapter Ends, A New One Begins
Digital ImageDigital finding ...
United Jewish Appeal of Greater New York
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Pulmonary Target Sign: A New Finding or a Neglected Feature? [PDF]
Saburi A, Colletti PM, Jafari R.
europepmc +1 more source
New York Governor William Averell Harriman with a group of United Jewish Appeal leaders
New York Governor William Averell Harriman (center) with a group of United Jewish Appeal leaders including Henry C. Bernstein, Jack D. Weiler, Samuel Leidesdorf, William Rosenwald, and Samuel Hausman at Inaugural Dinner.Digital ImageDigital finding ...
Gross, Emerich C.photographer +1 more
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

