Results 51 to 60 of about 2,585,786 (243)

Finding a heaviest vertex-weighted triangle is not harder than matrix multiplication [PDF]

open access: yes, 2009
We show that a maximum-weight triangle in an undirected graph with n vertices and real weights assigned to vertices can be found in time O(n(omega) + n(2+o(1))), where omega is the exponent of the fastest matrix multiplication algorithm. By the currently
Lingas, Andrzej,   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

One Chapter Ends, A New One Begins

open access: yes, 1986
Digital ImageDigital finding ...
United Jewish Appeal of Greater New York
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Pulmonary Target Sign: A New Finding or a Neglected Feature? [PDF]

open access: yesAcad Radiol, 2021
Saburi A, Colletti PM, Jafari R.
europepmc   +1 more source

New York Governor William Averell Harriman with a group of United Jewish Appeal leaders

open access: yes, 1955
New York Governor William Averell Harriman (center) with a group of United Jewish Appeal leaders including Henry C. Bernstein, Jack D. Weiler, Samuel Leidesdorf, William Rosenwald, and Samuel Hausman at Inaugural Dinner.Digital ImageDigital finding ...
Gross, Emerich C.photographer   +1 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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