Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Role of epiregulin levels in polycystic ovary syndrome patients: new findings and clinical significance. [PDF]
Topsakal S +4 more
europepmc +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
New Findings on the Hosts and Distribution of <i>Eustrongylides excisus</i> (Nematoda: Dioctophymatidae) and Other Zoonotic Parasites in Fish Species from an Uninvestigated Subalpine Lake, Varese Lake (Northwestern Italy). [PDF]
Macrelli M +7 more
europepmc +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
2024: The year in cardiovascular disease - the year of lipoprotein(a). Research advances and new findings. [PDF]
Sosnowska B +5 more
europepmc +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Second Scope, New Findings: Pediatric Stridor Is Not Always Due to Croup or Laryngomalacia: A Case Report. [PDF]
Ghaith S, Hsu D, Dixon W.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The role of the beta cell in type 2 diabetes: new findings from the last 5 years. [PDF]
Yau B +4 more
europepmc +1 more source

