Results 191 to 200 of about 4,415,878 (242)

New findings of <i>Dunyu</i> (Eugaleaspiformes, Galeaspida) from the Xiaoxi Formation in South China and their biostratigraphic significance. [PDF]

PeerJ
Li Q, Shan X, Gai Z, Chen Y, Peng L, Zheng J, Lin X, Zhao W, Zhu M.   +8 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

New findings on clinical experience on surface-guided radiotherapy for frameless non-coplanar stereotactic radiosurgery treatments. [PDF]

J Appl Clin Med Phys
Sánchez-Rubio P, Rodríguez-Romero R, Pinto-Monedero M, Alejo-Luque L, Martínez-Ortega J.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

New Findings in Prominent Lower Eyelid Fat Pads Possibly Contributing to Their Etiology: Two Prospective Studies. [PDF]

Plast Reconstr Surg Glob Open
Sweis IE, Cressey BC.
europepmc   +1 more source

New findings of dermoscopy and reflectance confocal microscopy for perforating pseudoxanthoma elasticum with elastosis perforans serpiginosa-like changes. [PDF]

JAAD Case Rep
Zhao J, Li R, Sun H, Duan Y.
europepmc   +1 more source

Health Risk Factors and ADHD: New Findings From the Community-Based Replication Project to Learn About Youth-Mental Health (Re-PLAY-MH). [PDF]

J Atten Disord
Katz SM, de Arellano A, Rother Y, Levine S, Claussen AH, Danielson ML, Flory K.   +6 more
europepmc   +1 more source