Results 51 to 60 of about 4,415,225 (242)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
New findings of Deltocephalinae (Hemiptera, Cicadellidae) from Pakistan [PDF]
The genus Cicadula Zetterstedt is reported for the first time from Pakistan with a newly recorded Cicadula simlaensis Viraktamath & Yeshwanth. In addition, Platymetopius fidelis (Distant) is also rediscovered from Pakistan and studied here.
Bismillah Shah +5 more
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
New Findings in Thyroid Disease [PDF]
From the foundations into clinical practice" – this was the motto of the German thyroid experts’ symposium in Heidelberg on 10 to 13 October 2007, a biennial event organized by the German Society of Nuclear Medicine (DGN), the German Society of Endocrinology (DGE), and the German Society of Surgery (DGCH).
Frank, Grünwald, Marcus, Middendor
openaire +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
New Findings Regarding Sarcopenia Biomarkers
Sarcopenia is prevalent among the elderly.The incidence of this condition rises with advancing age,posing danger and lacking effective therapeutic options.Hence,timely detection is crucial.Enhancing the ability to identify biomarkers with high ...
Yanjiao Zhao, Hongmei Wang
doaj +1 more source
STAR POLYMER/WATER SOLUTIONS: NEW EXPERIMENTAL FINDINGS
The purpose of the present work is to highlight a number of recent experimental results that have contributed significantly to the research area of star polymer.
C.Branca, S.Magazu, F.Migliardo
doaj +1 more source

