Results 51 to 60 of about 4,415,225 (242)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

New findings of Deltocephalinae (Hemiptera, Cicadellidae) from Pakistan [PDF]

open access: yesJournal of Insect Biodiversity and Systematics, 2023
The genus Cicadula Zetterstedt is reported for the first time from Pakistan with a newly recorded Cicadula simlaensis Viraktamath & Yeshwanth. In addition, Platymetopius fidelis (Distant) is also rediscovered from Pakistan and studied here.
Bismillah Shah   +5 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

New Findings in Thyroid Disease [PDF]

open access: yesDeutsches Ärzteblatt international, 2008
From the foundations into clinical practice" – this was the motto of the German thyroid experts’ symposium in Heidelberg on 10 to 13 October 2007, a biennial event organized by the German Society of Nuclear Medicine (DGN), the German Society of Endocrinology (DGE), and the German Society of Surgery (DGCH).
Frank, Grünwald, Marcus, Middendor
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

New Findings Regarding Sarcopenia Biomarkers

open access: yesGuoji laonian yixue zazhi
Sarcopenia is prevalent among the elderly.The incidence of this condition rises with advancing age,posing danger and lacking effective therapeutic options.Hence,timely detection is crucial.Enhancing the ability to identify biomarkers with high ...
Yanjiao Zhao, Hongmei Wang
doaj   +1 more source

STAR POLYMER/WATER SOLUTIONS: NEW EXPERIMENTAL FINDINGS

open access: yesCondensed Matter Physics, 2002
The purpose of the present work is to highlight a number of recent experimental results that have contributed significantly to the research area of star polymer.
C.Branca, S.Magazu, F.Migliardo
doaj   +1 more source

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