Results 171 to 180 of about 18,947,439 (256)

Recentering Resource-Based Livelihoods: Prosperity Beyond Extractivism and Pastoralism. [PDF]

Can Rev Sociol
Curley E.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Medical Humanities in the Nordics. [PDF]

J Med Humanit
Söderfeldt Y, Bodin M, Hansson K.
europepmc   +1 more source

Humanities Center Flipbook 2024-25

Table of Contents: Welcome Meet the Fellows The New Humanities Center small Talks Humanities Center Co-Sponsored Event/Activity Grants Faculty-Student Enrichment Grants Faculty Project Grants Faculty Speakers Conference Travel Research Support ...
Humanities Center,
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Why do reviewers disagree? Evidence from four funders and 134,000 reviews. [PDF]

PLoS One
Hesselberg JO, Ulleberg P, Sørensen Ø, Fostervold KI, Ingvaldsen SH, Svege I.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Matilda of Tuscany-Canossa: Commemorating the 9th Centennial of the Great Countess, IV

Storicamente, 2017
Valerie Eads, Edward Coleman, David Hay, Robert Houghton, John Oastler Ward, Penelope Nash, Helen Nicholson   +6 more
doaj   +1 more source

Humanistic thought in medical dao: a cross-cultural perspective of global medical humanities. [PDF]

Philos Ethics Humanit Med
Li Y, Cheng Y.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source