Results 11 to 20 of about 199,336 (299)

Evaluation and Treatment of Cardiac Tamponade in a Pregnant Patient

Case Reports in Obstetrics and Gynecology, 2020
Cardiac tamponade is an uncommon but life-threatening emergency that may occur in pregnant women. There is a plethora of causes, but prompt diagnosis and intervention is imperative to optimize both maternal and fetal outcomes.
Matthew P. Romagano, Krunal Patel, Shauna Williams, Joseph J. Apuzzio   +3 more
doaj   +1 more source

Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

Journal for ImmunoTherapy of Cancer, 2019
Background ONC201 is a small molecule antagonist of DRD2, a G protein-coupled receptor overexpressed in several malignancies, that has prolonged antitumor efficacy and immunomodulatory properties in preclinical models.
Mark N. Stein, Jyoti Malhotra, Rohinton S. Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert D. Aiken, Tina Mayer, Bruce G. Haffty, Jenna H. Newman, Salvatore M. Aspromonte, Praveen K. Bommareddy, Ricardo Estupinian, Charles B. Chesson, Evita T. Sadimin, Shengguo Li, Daniel J. Medina, Tracie Saunders, Melissa Frankel, Aparna Kareddula, Sherrie Damare, Elayne Wesolowsky, Christian Gabel, Wafik S. El-Deiry, Varun V. Prabhu, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Joseph R. Bertino, Steven K. Libutti, Janice M. Mehnert, Andrew Zloza   +33 more
doaj   +1 more source

Marked Sinus Bradycardia Associated With Remdesivir in COVID-19

JACC: Case Reports, 2020
Remdesivir has seen extensive use during the coronavirus disease-2019 pandemic given its clinically proven efficacy against severe acute respiratory syndrome coronavirus type 2. There has been little cited regarding adverse effects.
James C. Gubitosa, DO, Parul Kakar, MD, Christine Gerula, MD, Hernando Nossa, MD, Diana Finkel, MD, Kristin Wong, MD, Megna Khatri, MD, Hasan Ali, DO   +7 more
doaj   +1 more source

Validation of the Diabetomics CovAB SARS-CoV-2 antibody test in children: comparison with serology

Microbiology Spectrum
Monitoring antibody prevalence is a valuable tool to evaluate the burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a community, identify risk factors, and assess the impact of clinical and public health intervention strategies ...
Manisha Gurumurthy, Joseph Schwab, Sri Ram Pentakota, Rahul Ukey, Maria Gennaro, Pauline Thomas, Stephen Friedman   +6 more
doaj   +1 more source

The Impact of Interdisciplinary Education on Skills and Attitudes of Surgery and Emergency Medicine Residents

The Surgery Journal, 2019
Background Interdisciplinary education (IDE) has been proposed as a means to improve patient safety by enhancing the performance of diverse health care teams. The improved camaraderie between members of different specialties may enhance communication and
Anastasia Kunac, Neil A. King, Ilya Ostrovsky, David Rytzarev, Aziz M. Merchant, Tiffany Murano   +5 more
doaj   +1 more source

Components of diabetes prevalence in Denmark 1996–2016 and future trends until 2030

BMJ Open Diabetes Research & Care, 2020
Introduction Incidence rates of diabetes have been increasing and mortality rates have been decreasing. Our aim is the quantification of the effects of these on the prevalence and prediction of the future burden of diabetes.Research design and methods ...
Kevin M Tveter, Jose A Villa-Rodriguez, Alrick J Cabales, Fiona G Bawagan, Rocio M Duran, Diana E Roopchand   +5 more
doaj   +1 more source

Polyphenol-induced improvements in glucose metabolism are associated with bile acid signaling to intestinal farnesoid X receptor

BMJ Open Diabetes Research & Care, 2020
Introduction Bile acid (BA) biotransformation by gut bacteria impacts BA profile and signaling to nuclear receptors, such as the farnesoid X receptor (FXR) regulating glucose metabolism.
Kevin M Tveter, Jose A Villa-Rodriguez, Alrick J Cabales, Fiona G Bawagan, Rocio M Duran, Diana E Roopchand   +5 more
doaj   +1 more source

ITI-signals and prelimbic cortex facilitate avoidance acquisition and reduce avoidance latencies, respectively, in male WKY rats

Frontiers in Behavioral Neuroscience, 2014
As a model of anxiety disorder vulnerability, male Wistar-Kyoto (WKY) rats acquire lever-press avoidance behavior more readily than outbred Sprague Dawley rats, and their acquisition is enhanced by the presence of a discrete signal presented during the ...
Kevin D Beck, Kevin D Beck, Kevin D Beck, Xilu eJiao, Xilu eJiao, Xilu eJiao, Ian M. Smith, Ian M. Smith, Catherine E Myers, Catherine E Myers, Catherine E Myers, Kevin ePang, Kevin ePang, Kevin ePang, Richard J Servatius, Richard J Servatius, Richard J Servatius   +16 more
doaj   +1 more source

Stroke in COVID-19: a single-centre initial experience in a hotspot of the pandemic

Stroke and Vascular Neurology, 2020
Background COVID-19, caused by SARS-CoV-2, is a global pandemic that has been an immense burden on healthcare systems all over the world. These patients may be at higher risk for acute ischaemic stroke (AIS).
Pratit Patel, Priyank Khandelwal, Ivo Bach, Pratibha Surathi, Nora Montealegre, Osama Abu-Hadid, Sara Rubenstein, Sviatoslav Redko, Siddharth Gupta, Machteld Hillen, Adham Kamel   +10 more
doaj   +1 more source

Abstract 127: Delayed Thrombectomy In A Patient With Recurrent MCA Strokes

Stroke: Vascular and Interventional Neurology, 2023
Introduction Prior research has demonstrated mechanical thrombectomy (MT) to be a safe and effective treatment for stroke patients with a large vessel occlusion (LVO).1 However, MT has generally only been studied in a time window of less than 24 hours.2 ...
Pradeep Joseph, Ivo Bach, Priyank Khandelwal   +2 more
doaj   +1 more source