Results 201 to 210 of about 18,332,124 (367)

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla   +16 more
wiley   +1 more source

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis   +6 more
wiley   +1 more source

Racial discrepancies in presentation of hospitalized infantile hemangioma cases using the Kids' Inpatient Database

open access: yesHealth Science Reports, 2023
Keshav D. Kumar   +3 more
doaj   +1 more source

Evolutionary Insight into the Association between New Jersey Polyomavirus and Humans. [PDF]

open access: yesViruses, 2023
Aghebatrafat AA   +8 more
europepmc   +1 more source

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