Results 61 to 70 of about 199,336 (299)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Modified 5‐Item Frailty Index and Postoperative Outcomes Following Parotidectomy for Malignancy

Laryngoscope Investigative Otolaryngology
Objective Frailty is a predictor of poor outcomes following surgery for malignancy. Our study investigates the association between the modified 5‐item frailty index (mFI‐5) and postoperative outcomes following parotidectomy for malignancy.
Ariana L. Shaari, Keshav Kumar, Anthony M. Saad, Aman M. Patel, Paul Cowan, Andrey Filimonov, Ghayoour S. Mir   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

5 Cliches About new usa nike soccer jersey cheap You Should Avoid

, 2022
e3xhmrn031
openalex   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages

mSphere, 2017
During tuberculosis, macrophages are critical for both pathogen survival and host immune activation. Since expression of particular cell surface markers reflects cell function, we used flow cytometry to measure the abundance of surface markers associated
Karim Lakehal, David Levine, Kathleen F. Kerr, Pooja Vir, Natalie Bruiners, Alfred Lardizabal, Maria Laura Gennaro, Richard Pine   +7 more
doaj   +1 more source

Aeromagnetic map of the Chatham and parts of the Roselle and Plainfield quadrangles, Morris, Union, Essex, and Somerset Counties, New Jersey [PDF]

, 1958
John R. Henderson, Natalie S. Tyson, Sybil Gilchrist   +2 more
openalex   +1 more source

Catapleura Cope, 1870 is Euclastes Cope, 1867 (Testudines: Pan-Cheloniidae): synonymy revealed by a new specimen from New Jersey

, 2021
Paul V. Ullmann, M. Eric Carr
openalex   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source

Diagnosis and Management of Retrograde Cricopharyngeal Dysfunction: A Systematic Review

OTO Open
Objective Retrograde cricopharyngeal dysfunction (R‐CPD) is a syndrome with rapidly increasing awareness since being first described in March 2019. As such, few cases of R‐CPD are currently reported in the literature. The goal of this study is to provide
Raj Malhotra, Hamza Khan, Sydney Zaransky, Joseph Celidonio, Kenneth Yan, Rachel Kaye   +5 more
doaj   +1 more source