Results 51 to 60 of about 3,903 (254)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A Bonaventurian rousing of the metaphysics of primary causality to counter New Materialism
HTS Teologiese Studies/Theological StudiesBonaventure discerned the continuous presence of the problem of primary causality in contingent beings. From his perspective, full knowledge of the problem of primary causality emerges only when human reason is reduced to the first cause.
Callum D. Scott
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Potíže s hmotou: Judith Butler a/nebo nový materialismus? [PDF]
Gender a Výzkum, 2013 The article presents the contemporary feminist stream of new materialism, and compares and contracts it with the linguistic branch of poststructuralism which has been criticized by new materialism for neglecting matter.
Hana Porkertová
doaj
Sanglap: Journal of Literary and Cultural Inquiry, 2021 This introduction attempts to briefly trace the diverse cartographies and philosophical lineages of new materialism. It charts their multidirectional, multispecies, multidisciplinary orientations in the attempt to liberate conceptualizations of matter ...
Subro Saha
doaj
New-Materialism and Reification in the Infoproduction Era
communication +1, 2013 Deleuze’s works on cinema established a parallel between the evolution of cinematographic narrative spaces and the development of non-Euclidean geometries, and contributed to the overcoming of the structuralistic approach to the analysis of ...
German A. Duarte
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mangrovian Encounters between Epistemologies of the South and New (Feminist) Materialism
eTropic: electronic journal of studies in the tropics, 2022 With the increased interest sparked across academia in both new materialism and epistemologies of the South, old colonial and patriarchal habits rear their vicious heads.
Aleida Luján Pinelo
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source