Results 81 to 90 of about 7,091,293 (301)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Impact of Chatbots on Adolescent Mental Health Development: A Comprehensive Literature Review

open access: yesJournal of Multidisciplinary Healthcare
Yidong Wu,1,* Tong Wu,2,* Kerun Zhu,3 Xinyu Liu,3 Jiarui Liu,3 Yuyan Wang,3 Ruojin Shi,3 Jia Xiong,3 Xinyue Xing,3 Yao Lv,3 Yaohong Niu,3 Min Peng,4 Xingyan Du1 1School of Journalism and Communication, Lanzhou University, Lanzhou, 730000,
Wu Y   +12 more
doaj  

Elaboration of New Method of Deep Processing of Caro-tene-containing Raw Materials Into Nanoadditives with the Use of Cryogenic Freezing and Fine-dispersed Grinding [PDF]

open access: yes, 2016
The aim of the work is elaboration of principally new cryogenic method of deep processing of carotene-containing vegetable raw material (CCVRM) such as carrot, pumpkin, sweet Bulgarian pepper, tomato, sea buckthorn, apricot using cryogenic freezing and ...
Bilenko, L. (Leonida)   +4 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

New media practices in India: bridging past and future, markets and development [PDF]

open access: yes, 2011
This article provides a review of the academic and popular literature on new media practices in India, focusing on the country’s youth's use of mobile phones and the Internet, as well as new media prosumption. One particular feature of the Indian case is
Schwittay, Anke
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Impedance-Modulating Patch Integration for Gain and Bandwidth Control of Antenna-in-Display in Millimeter-Wave Smartphones [PDF]

open access: yesJournal of Electromagnetic Engineering and Science
In this study, an impedance-modulating patch (IMP) antenna-in-display (AiD) scheme is introduced to enable on-demand modification of the antenna operating frequency, bandwidth, and gain by selectively laminating a film with a printed IMP onto a pre ...
Byeongjin Kim   +3 more
doaj   +1 more source

MEDIA MARKET: NEW MEDIA

open access: yesVestnik Bishkek state university af K Karasaev
This article explores the essence and economic content of the modern media market, emphasizing the global emergence of new media. It defines new media, contrasts it with traditional outlets such as television, radio, and newspapers, and structures its main features, including its advantages and disadvantages.
openaire   +1 more source

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