Results 171 to 180 of about 4,232,965 (395)

The Romanian Media - An Overview [PDF]

open access: yes
The Romanian Media Sector from the last 17 years can be described as a dinamic one. In the current study, which is also a part of national report of the Grundtvig 2 project "The Influence of Media in Adult Education Development" 06-G2-94-TM-RO-C, we ...
Laura MALITA
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Education remix: New media, literacies, and the emerging digital geographies [PDF]

open access: yes, 2010
This article explores instances of youth educating themselves beyond the boundaries of school through engagement with and production of “digital geographies,” or the emerging landscapes that are being produced through the confluence of new communicative ...
Lalitha Vasudevan
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

New generation, new media and a new education?

open access: yes, 2012
Neue Generation, neue Medien und eine neue Bildung? Theo Bastiaens & Claudia Schrader Abstract This chapter focuses on the question of what influence societal changes have on learners, their learning behavior and the curriculum. Fact is that there has been one major change with an enormous impactand that is the shift towards a network society ...
Bastiaens, Theo, Schrader, Claudia
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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