Results 161 to 170 of about 251,261 (256)

Discovery of a novel lymphocytic choriomeningitis virus strain associated with severe human disease in immunocompetent patient, New Mexico. [PDF]

Emerg Microbes Infect
Gass JT, Nofchissey RA, Twohig FM, Ye C, Goodfellow SM, Mentore K, Burgos M, Negrete O, Whitmer S, Klena JD, Cannon D, Sayyad L, Bradfute SB.   +12 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Novel Bat Adenovirus Closely Related to Canine Adenoviruses Identified via Fecal Virome Surveillance of Bats in New Mexico, USA, 2020-2021. [PDF]

Viruses
Weary TE, Zhou LH, MacDonald L, Ibañez Iv D, Jaramillo C, Dunn CD, Wright TF, Hanley KA, Goldberg TL, Orr TJ.   +9 more
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Genome Sequences of Bacteriophages Natasha and RustyBoy, Isolated on <i>Arthrobacter globiformis</i> , and Fazel, Isolated on <i>Gordonia rubripertincta</i> in Southwestern New Mexico. [PDF]

MicroPubl Biol
Merchant R, Kirk V, McClish I, Ferrara M, Garcia L, Oesch R, Barrera-Moncayo I, Blair A, Eaton E, Gatto G, Geoffrion L, Kirkman M, Kouchich-Martens A, Madduri L, Rosa S, Valdez M, Zamora A, DeVeaux L, Jobe N, Goncz K.   +19 more
europepmc   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

The Epidemiology of Coccidioidomycosis (Valley fever) and the Disease Ecology of <i>Coccidioides</i> spp. in New Mexico (2006-2023). [PDF]

Pathogens
Salazar-Hamm PS, Shrum Davis S, Catalán-Dibene J, Romero-Olivares AL, Edge K, Bartlow AW, Natvig DO, Gorris ME.   +7 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Overcoming barriers to care for individuals with fetal alcohol spectrum disorder: challenges and solutions in New Mexico and beyond. [PDF]

Front Pediatr
Gibson AC, Velhagen JM, Jaffe T, Hill DE, Moriarta ML, Valenzuela CF.   +5 more
europepmc   +1 more source

Cooperative learning strategies to raise attainment in mathematics with pupils aged 11–16 years: A systematic literature review

British Educational Research Journal, EarlyView.
Abstract Cooperative learning is a widely adopted teaching method to improve academic achievement. This review synthesises existing research on the use of cooperative learning within a school setting for pupils aged 11–16 years. Such a review has not been undertaken to date and will present an evidence base for educators considering implementation ...
Patricia Hampson, Zhe. Li, Allen Thurston   +2 more
wiley   +1 more source