Results 41 to 50 of about 26,412,925 (153)

Stratification by a polygenic risk score of common variation aids in Alzheimer's disease rare variant discovery

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION We utilized an Alzheimer's disease (AD) polygenic risk score (PRS) to discover associations with novel rare variants (RVs). METHODS PRSs for European ancestry (EA) participants of the Alzheimer's Disease Sequencing Project were calculated using summary statistics from a large genome‐wide association study.
Oluwatosin Olayinka   +13 more
wiley   +1 more source

The Amish Settlement in Honduras, 1968-1978: A (Half) Failed Attempt to Develop an Amish Understanding of Mission

open access: yesThe Journal of Amish and Plain Anabaptist Studies, 2016
For their several-hundred years of successfully maintaining Amish settlements in North America, for what reason would a group of families—largely from Nappanee, IN, and Aylmer, ON—want to start a settlement in Honduras? This account traces the genesis of
Cory Anderson
doaj  

Genetic Linkage for Bipolar Disorder to the Distal Region of Chromosome 19q: A Large Family Whole Genome Sequencing Study

open access: yesBipolar Disorders, Volume 28, Issue 4, June 2026.
ABSTRACT Background Bipolar disorder (BD) is among the most heritable psychiatric disorders, with a genetic architecture likely consisting of both common genetic variants with small effects and rare variants with strong effects in certain families or populations.
Albert H. C. Wong   +8 more
wiley   +1 more source

The Amish Symposium [PDF]

open access: yes, 2019
The Amish is a 500-some page university press-sized handbook that touches on a variety of topical areas. The book is the culmination of two and a half decades each of Kraybill’s, Johnson-Weiner’s, and Nolt’s work about the Amish.
Reschly, Steven   +3 more
core   +1 more source

Synaptic biomarkers in Alzheimer's disease dementia and mild cognitive impairment: A systematic review and meta‐analysis

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by synaptopathy, a neuropathological feature that can contribute to underlying cognitive decline. Here, we evaluate potential cerebrospinal fluid (CSF) and blood‐based synaptic biomarkers in AD dementia and its earliest clinical stage, mild cognitive impairment (MCI). METHODS Articles that
Amish Gaur   +10 more
wiley   +1 more source

Amish : drömmarnas utopi?

open access: yes, 2001
Denna C-uppsats är en deskriptiv studie av Amishfolket. Uppsatsens syfte är att ge läsaren en ingående beskrivning av Amish. Eftersom Amish består av många olika grupperingar är det, Old Order Amish, det vill säga den ursprungliga och mest konservativa ...
Olofsson, Joanna
core   +2 more sources

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld   +5 more
wiley   +1 more source

Constitutive Disorder As Method: A Multilingual Dictionary From Within the Camp

open access: yesPopulation, Space and Place, Volume 32, Issue 4, May 2026.
ABSTRACT This article analyzes Multilingual Dictionary – Living Together in a Refugee Camp, a co‐research project documenting words and expressions created, invented, and circulated among migrant communities in the Moria and Mavrovouni camps on Lesvos Island between 2018 and 2022.
Nagehan Uskan
wiley   +1 more source

Intracellular protein GBF1 displays significant associations with amyloid pathology in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Despite the identification of familial Alzheimer's disease (FAD) genes and neuropathological alterations, AD displays complex genetic heterogeneity and molecular pathogenesis that warrant further investigation. GBF1 (Golgi brefeldin A resistant guanine nucleotide exchange factor 1) regulates protein trafficking, and genetic ...
Sean J. Miller   +16 more
wiley   +1 more source

Explaining Anabaptist Persistence in the Modern Economy: Past Paradigms and New Institutional Theory

open access: yesThe Journal of Amish and Plain Anabaptist Studies, 2017
Amish and plain Anabaptist economic research has focused either on the religious ethic in the tradition of Weber—religious convictions drive economic behavior—or the ethnic resources model—resources are mobilized to entrepreneurship.
Martin Lutz
doaj  

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