Results 191 to 200 of about 5,305,995 (318)
A diversity-based approach to requirements tracing in new product development. [PDF]
Production models emerged in recent times have stressed the need to face complex production contexts, characterized in particular by the rise in internal and environmental variability.
Loris Gaio
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dataset on graphite nanoplatelet enhanced HDPE composites: An ensemble machine learning approach estimating the tensile modulus, toughness, and hardness thus creating a roadmap for new product development. [PDF]
Data BriefBadgayan ND, Sahu SK, Kundu A, Kundu SG.
europepmc +1 more source
New Product Development in an Omnichannel World
, 2019 Robert P. Rooderkerk, Santiago Gallino
openalex +1 more source
Understanding consumer needs and preferences in new product development: the case of functional food innovations [PDF]
As the majority of new products fail it is important to focus on the needs and preferences of the consumers in new product development. Consumers are increasingly recognised as important co-developers of innovations, often developing new functions for ...
Ellen H.M. Moors, Rogier Donders
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Teaching New Product Development to Design Led Innovation
, 2013 Cara Wrigley, Sam Bucolo
openalex +2 more sources
NEW PRODUCT DEVELOPMENT PRACTICES OF THE U.S. CONFECTIONERY MANUFACTURERS: 2006 SURVEY PRELIMINARY FINDINGS [PDF]
This paper reports on the new product development practices of the U.S. confectionery manufacturers. A mail survey method was used to collect data. Confectionery manufacturers, specifically, new product development managers listed in the Thomas Food and ...
Spaulding, Aslihan D.
core +1 more source